Expression of SOCS3

Stable Identifier
R-HSA-9005340
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
STAT3 induce expression of genes after IL24 stimulus
ReviewStatus
5/5
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Expression of SOCS3
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Overexpression and production of Suppressor of cytokine signaling 3 (SOCS3) has been reported after Interleukin 24 (IL24) stimulus (Andoh et al. 2009, Uto-Konomi et al. 2012).
This is a black box event since details about the binding to DNA, transcription and translation are omitted.
Literature References
PubMed ID Title Journal Year
19535621 Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease

Bamba, S, Kim-Mitsuyama, S, Andoh, A, Fujiyama, Y, Nishida, A, Tsujikawa, T, Shioya, M

J. Immunol. 2009
Participants
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Output
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This event is regulated
Positively by
Regulator
2xp-STAT3 [nucleoplasm] (Homo sapiens)
Authored
Duenas, C  (2017-03-16)
Reviewed
Datta, SK  (2017-11-15)
Created
Duenas, C  (2017-05-08)
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