CITED1 and EP300 bind ESR1:estrogen:TGFA gene promoter

Stable Identifier
R-HSA-9008271
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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CITED1 and EP300 contribute to the estrogen-dependent expression of the TGFA gene. CITED1 (also known as CBP) interacts directly with ESR1 through the transcriptional activation AF2 domain and enhances its activity. The interaction between ESR1 and exogenous CITED1 also stabilizes the interaction with EP300 (Yahate et al, 2001).

Literature References
PubMed ID Title Journal Year
11581164 Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein

Yahata, T, Shao, W, Endoh, H, Hur, J, Coser, KR, Sun, H, Ueda, Y, Kato, S, Isselbacher, KJ, Brown, M, Shioda, T

Genes Dev. 2001
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created