Binding of Malectin

Stable Identifier
R-HSA-901006
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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A recently discovered protein called malectin is known to recognize the Glc(2)Man(9)GlcNAc(2) glycan (Schallus T et al, 2008). The exact role of this interaction is not clear but malectin is thought to regulate the availability of this substrate to glucosidase II, or to act as a chaperone to stabilize the unfolded protein.

Literature References
PubMed ID Title Journal Year
18524852 Malectin: a novel carbohydrate-binding protein of the endoplasmic reticulum and a candidate player in the early steps of protein N-glycosylation

Schallus, T, Jaeckh, C, Fehér, K, Palma, AS, Liu, Y, Simpson, JC, Mackeen, M, Stier, G, Gibson, TJ, Feizi, T, Pieler, T, Muhle-Goll, C

Mol Biol Cell 2008
Participants
Participant Of
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