Reactome | LHX4 [nucleoplasm]

LHX4 [nucleoplasm]

Stable Identifier

R-HSA-9010585

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

LIM/homeobox protein Lhx4, LHX4_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q969G2 LHX4

Gene Names

LHX4

Chain

chain:1-390

Reference Genes

BioGPS Gene:89884 LHX4

COSMIC (genes):LHX4 LHX4

CTD Gene:89884 LHX4

dbSNP Gene:89884 LHX4

ENSEMBL:ENSG00000121454 LHX4

ENSEMBL_homo_sapiens_GENE:ENSG00000121454.6 LHX4

HGNC:21734 LHX4

KEGG Gene (Homo sapiens):89884 LHX4

Monarch:89884 LHX4

NCBI Gene:89884 LHX4

OMIM:602146 LHX4

UCSC:Q969G2 LHX4

Reference Transcript

RefSeq:NM_033343.3 LHX4

Other Identifiers

11740405_at

11740406_at

1553156_PM_at

1553156_at

1553157_PM_at

1553157_at

16674540

232781_PM_at

232781_at

2370033

2370034

2370035

2370038

2370054

2370055

2370057

2370058

2370060

2370061

2370062

2370063

2370065

2370067

57414_at

7907849

89884

A_14_P116523

A_23_P23869

A_32_P310219

GO:0000785

GO:0000977

GO:0000981

GO:0001228

GO:0001890

GO:0003677

GO:0005515

GO:0005634

GO:0005694

GO:0006351

GO:0006355

GO:0006357

GO:0006915

GO:0008045

GO:0008327

GO:0009887

GO:0012501

GO:0021526

GO:0030154

GO:0030182

GO:0043066

GO:0043226

GO:0043565

GO:0045944

GO:0046872

GO:0048856

GO:0140110

GO:1990837

HMNXSV003007241

Hs.120127.0.S1_3p_at

Hs2.152082.1.S1_3p_at

Hs2.152082.1.S2_3p_at

ILMN_1674366

PH_hs_0006630

PH_hs_0023260

TC01001561.hg

Participates

as a component of

ISL1:LHX4:LDB1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_203129.1

OpenTargets

ENSG00000121454

GeneCards

Q969G2

HPA

ENSG00000121454-LHX4

Ensembl

ENSP00000263726, ENST00000263726, ENSG00000121454

PRO

Q969G2

Pharos - Targets

Q969G2

Orphanet

16786

PDB

5HOD

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y5N6 ORC6	4	ORC6 [nucleoplasm] (R-HSA-68539) ORC6 [cytosol] (R-HSA-9734663) p-T195-ORC6 [cytosol] (R-HSA-9734682) p-T195-ORC6 [nucleoplasm] (R-HSA-9734715)	0.781	8
UniProt:P61371 ISL1	1	ISL1 [nucleoplasm] (R-HSA-400478)	0.667	3
UniProt:O75604 USP2	2	USP2 [cytosol] (R-HSA-5212661) USP2 [nucleoplasm] (R-HSA-5689946)	0.666	4
UniProt:P25490 YY1	1	YY1 [nucleoplasm] (R-HSA-4086091)	0.659	4
UniProt:P36404 ARL2	2	ARL2 [mitochondrial matrix] (R-HSA-5250216) ARL2 [cytosol] (R-HSA-5216230)	0.556	3
UniProt:O15169 AXIN1	11	AXIN1 L396M [cytosol] (R-HSA-5251503) AXIN1 Y346* [cytosol] (R-HSA-4839753) AXIN1 E406* [cytosol] (R-HSA-5251500) AXIN1 W247* [cytosol] (R-HSA-5251512) AXIN1 P354L [cytosol] (R-HSA-5251511) AXIN1 P255S [cytosol] (R-HSA-5251505) ub-AXIN1 [cytosol] (R-HSA-4641133) Ub-RibC-AXIN1 [cytosol] (R-HSA-3640864) AXIN1 [cytosol] (R-HSA-195249) p-T481,S486,S493-AXIN1 [cytosol] (R-HSA-206040) RibC-AXIN1 [cytosol] (R-HSA-3640841)	0.556	3
UniProt:O00712 NFIB	1	NFIB [nucleoplasm] (R-HSA-60136)	0.471	2
UniProt:Q12857 NFIA	1	NFIA [nucleoplasm] (R-HSA-60134)	0.471	2

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