Proteasome degrades ubiquitinated ROBO3.1

Stable Identifier
R-HSA-9011313
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
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Based on studies using recombinant C. elegans proteins expressed in human 293T cells, ZSWIM8-mediated ubiquitination of ROBO3.1 targets ROBO3.1 for proteasome-mediated degradation (Wang et al. 2013).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
endopeptidase activity of 26S proteasome [cytosol]
Physical Entity
Activity
Inferred From
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