GREB1 translation is negatively regulated by miR-26A and B

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R-HSA-9011961
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Reaction [omitted]
Species
Homo sapiens
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Translation of GREB1 mRNA is negatively regulated by direct binding of mIR-26A and mIR-26B to the 3' UTR. mIR-26 expression is itself negatively regulated in response to estrogen in a manner that depends on estrogen-stimulated MYC gene expression (Tan et al, 2014).

Literature References
PubMed ID Title Journal Year
24735615 Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2

Tan, S, Ding, K, Li, R, Zhang, W, Li, G, Kong, X, Qian, P, Lobie, PE, Zhu, T

Breast Cancer Res. 2014
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