CHD1 translation is negatively regulated by miR-26A and B

Stable Identifier
R-HSA-9012186
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Translation of CHD1 is negatively regulated by binding of mIR-26A and mIR-26B to the 3'UTR. Estrogen-and MYC-dependent CHD1 expression contributes to the proliferative response to estrogen stimulation (Tan et al, 2014).

Literature References
PubMed ID Title Journal Year
24735615 Identification of miR-26 as a key mediator of estrogen stimulated cell proliferation by targeting CHD1, GREB1 and KPNA2

Tan, S, Ding, K, Li, R, Zhang, W, Li, G, Kong, X, Qian, P, Lobie, PE, Zhu, T

Breast Cancer Res. 2014
Participants
Participant Of
This event is regulated
Authored
Reviewed
Created