NOTCH3 coactivator complex binds HES1 gene promoter

Stable Identifier
R-HSA-9013652
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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NOTCH3 coactivator complex binds HES1 gene promoter
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NOTCH3 coactivator complex, composed of at least NICD3 (NOTCH3 intracellular domain), RBPJ and MAML (MAML1, MAML2 or MAML3; possibly MAMLD1), directly binds to RBPJ elements in the HES1 gene promoter (Lin et al. 2002).
Participants
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Output
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as an event of
Event Information
Go Biological Process
positive regulation of transcription of Notch receptor target (0007221)
Inferred From
Notch3 coactivator complex binds Hes1 gene promoter (Homo sapiens)
Authored
Orlic-Milacic, M  (2017-09-20)
Reviewed
Haw, R  (2017-10-30)
Created
Orlic-Milacic, M  (2017-07-25)
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