MECP2 binds CRH gene promoter

Stable Identifier
R-HSA-9017983
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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MECP2 binds CRH gene promoter
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Based on studies in mice, MECP2 binds to the promoter of the CRH gene, encoding corticotropin-releasing hormone (corticoliberin) (McGill et al. 2006, Samaco et al. 2012). MECP2 preferentially binds to the CRH promoter with a repressive dimethylation of histone H3 (McGill et al. 2006).
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Mecp2 binds Crh gene promoter (Mus musculus)
Authored
Orlic-Milacic, M  (2017-10-02)
Reviewed
Krishnaraj, R  (2018-08-07)
Christodoulou, J  (2018-08-07)
Created
Orlic-Milacic, M  (2017-08-29)
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