Biosynthesis of D-series resolvins

Stable Identifier
R-HSA-9018676
Type
Pathway
Species
Homo sapiens
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Biosynthesis of D-series resolvins
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The D-series resolvins (RvD1-6) are biosynthesised from the precursor ω-3 fatty acid docosahexaenoic acid (DHA), either via aspirin-triggered cylcooxygenase catalysis (17(R) AT-RvDs) or via the lipoxygenase pathway (described here) forming the epimeric 17(S)-RvD1-6 resolvins (Serhan et al. 2014, Bannenberg & Serhan 2010).

Literature References
PubMed ID Title Journal Year
25359497 Lipid mediators in the resolution of inflammation

Serhan, CN, Chiang, N, Dalli, J, Levy, BD

Cold Spring Harb Perspect Biol 2014
20708099 Specialized pro-resolving lipid mediators in the inflammatory response: An update

Bannenberg, G, Serhan, CN

Biochim. Biophys. Acta 2010
Participants
Events
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Event Information
Go Biological Process
long-chain fatty acid biosynthetic process (0042759)
Orthologous Events
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Biosynthesis of D-series resolvins (Caenorhabditis elegans)
Biosynthesis of D-series resolvins (Canis familiaris)
Biosynthesis of D-series resolvins (Danio rerio)
Biosynthesis of D-series resolvins (Dictyostelium discoideum)
Biosynthesis of D-series resolvins (Drosophila melanogaster)
Biosynthesis of D-series resolvins (Gallus gallus)
Biosynthesis of D-series resolvins (Mus musculus)
Biosynthesis of D-series resolvins (Plasmodium falciparum)
Biosynthesis of D-series resolvins (Rattus norvegicus)
Biosynthesis of D-series resolvins (Saccharomyces cerevisiae)
Biosynthesis of D-series resolvins (Schizosaccharomyces pombe)
Biosynthesis of D-series resolvins (Sus scrofa)
Biosynthesis of D-series resolvins (Xenopus tropicalis)
Authored
Jassal, B  (2017-09-04)
Reviewed
Hansen, TV  (2018-02-21)
Created
Jassal, B  (2017-09-04)
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