Interleukin-27 signaling

Stable Identifier
R-HSA-9020956
Type
Pathway
Species
Homo sapiens
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Interleukin-27 (IL27) is a heterodimeric cytokine that contains Epstein-Barr virus–induced gene 3 (EBI3) and IL27p28 (IL27). It signals through a receptor composed of Interleukin-6 receptor subunit beta (IL6ST, gp130), which is utilized by many cytokines, and Interleukin-27 receptor subunit alpha (IL27RA, WSX-1, TCCR) (Yoshida & Hunter 2015).

Literature References
PubMed ID Title Journal Year
25861977 The immunobiology of interleukin-27

Yoshida, H, Hunter, CA

Annu. Rev. Immunol. 2015
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Participant Of
Event Information
Orthologous Events
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Created