Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
p-S68-ELF3 [nucleoplasm]
Stable Identifier
R-HSA-9021349
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Pre-NOTCH Expression and Processing (Homo sapiens)
Pre-NOTCH Transcription and Translation (Homo sapiens)
ELF3 binds NOTCH3 gene promoter (Homo sapiens)
p-S68-ELF3 [nucleoplasm] (Homo sapiens)
p-S68-ELF3:NOTCH3 gene [nucleoplasm] (Homo sapiens)
p-S68-ELF3 [nucleoplasm] (Homo sapiens)
NOTCH3 gene transcription (Homo sapiens)
p-S68-ELF3 [nucleoplasm] (Homo sapiens)
p-S68-ELF3:NOTCH3 gene [nucleoplasm] (Homo sapiens)
p-S68-ELF3 [nucleoplasm] (Homo sapiens)
PRKCI phosphorylates ELF3 (Homo sapiens)
p-S68-ELF3 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P78545 ELF3
Gene Names
ELF3, ERT, ESX, JEN
Chain
chain:1-371
Reference Genes
BioGPS Gene:1999 ELF3
COSMIC (genes):ELF3 ELF3
CTD Gene:1999 ELF3
dbSNP Gene:1999 ELF3
ENSEMBL:ENSG00000163435 ELF3
ENSEMBL_homo_sapiens_GENE:ENSG00000163435.16 ELF3
HGNC:3318 ELF3
KEGG Gene (Homo sapiens):1999 ELF3
Monarch:1999 ELF3
NCBI Gene:1999 ELF3
OMIM:602191 ELF3
UCSC:P78545 ELF3
Reference Transcript
RefSeq:NM_004433.4 ELF3
RefSeq:NM_001114309.1 ELF3
Other Identifiers
11717594_s_at
11717595_s_at
11751914_s_at
11755315_a_at
16675924
1999
201003_PM_x_at
201003_x_at
201510_PM_at
201510_at
208270_PM_s_at
208270_s_at
210827_PM_s_at
210827_s_at
229842_PM_at
229842_at
2375008
2375009
2375010
2375012
2375013
2375014
2375015
2375016
2375017
2375020
2375022
2375024
2375025
2375027
2375028
2375031
2375033
2375034
2375035
2375036
2375037
36959_at
40445_at
62536_at
78130_at
7908793
80594_at
A_23_P104188
A_33_P3258091
GE80150
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0001824
GO:0003677
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005794
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006954
GO:0009653
GO:0030154
GO:0030198
GO:0043226
GO:0043565
GO:0045892
GO:0045944
GO:0048856
GO:0060056
GO:0140110
GO:1990837
HMNXSV003038978
HMNXSV003043209
HMNXSV003058243
Hs.67928.0.A1_3p_at
ILMN_1738347
ILMN_1769201
PH_hs_0014660
PH_hs_0031289
TC01001670.hg
U49278_at
U73843_at
g12025659_3p_s_at
g1841524_3p_a_at
g2338755_3p_at
p33365
Participates
as an output of
PRKCI phosphorylates ELF3 (Homo sapiens)
as an input of
ELF3 binds NOTCH3 gene promoter (Homo sapiens)
as a component of
p-S68-ELF3:NOTCH3 gene [nucleoplasm] (Homo sapiens)
Other forms of this molecule
ELF3 [nucleoplasm]
Inferred To
phospho-ELF3 [nucleoplasm]
(Bos taurus)
phospho-ELF3 [nucleoplasm]
(Canis familiaris)
phospho-ELF3 [nucleoplasm]
(Sus scrofa)
phospho-elf3 [nucleoplasm]
(Xenopus tropicalis)
phospho-p-S68-ELF3 [nucleoplasm]
(Gallus gallus)
phospho-Elf3 [nucleoplasm]
(Mus musculus)
phospho-Elf3 [nucleoplasm]
(Rattus norvegicus)
phospho-svh-5 [nucleoplasm]
(Caenorhabditis elegans)
Modified Residues
Name
O-phospho-L-serine at 68
Coordinate
68
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001107781.1
,
NP_004424.3
OpenTargets
ENSG00000163435
HPA
ENSG00000163435-ELF3
GeneCards
P78545
Ensembl
ENSP00000356252
,
ENST00000367283
,
ENSP00000356253
,
ENSP00000352673
,
ENST00000367284
,
ENST00000359651
,
ENSG00000163435
PRO
P78545
Pharos - Targets
P78545
PDB
2E8P
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q16236 NFE2L2
13
p-S,T,S558-NFE2L2 [nucleoplasm]
(R-HSA-9795736)
p-S40, S344, S347- NFE2L2 [nucleoplasm]
(R-HSA-9762050)
p-S344, S347,T-NFE2L2 [nucleoplasm]
(R-HSA-9762048)
ub-p-S40, S335, S338- NFE2L2 [nucleoplasm]
(R-HSA-9762058)
ub-p-S335, S338,T-NFE2L2 [nucleoplasm]
(R-HSA-9762055)
ub-NFE2L2 [cytosol]
(R-HSA-9758077)
p-S40-18 AcK-NFE2L2 [nucleoplasm]
(R-HSA-9760018)
p-S,T-18 AcK-NFE2L2 [nucleoplasm]
(R-HSA-9760033)
NFE2L2 [cytosol]
(R-HSA-201566)
p-S,T-NFE2L2 [cytosol]
(R-HSA-8932311)
p-S40-NFE2L2 [cytosol]
(R-HSA-8932290)
p-S,T-NFE2L2 [nucleoplasm]
(R-HSA-9715110)
p-S40-NFE2L2 [nucleoplasm]
(R-HSA-9715109)
0.581
5
UniProt:Q04206 RELA
7
MeK310-RELA [nucleoplasm]
(R-HSA-8865233)
p-S536-RELA [nucleoplasm]
(R-HSA-9861499)
p-S276,5xAcK-RELA [nucleoplasm]
(R-HSA-5660642)
p-S276-RELA [nucleoplasm]
(R-HSA-5624468)
polySUMO3-K37,K122,K123-RELA [nucleoplasm]
(R-HSA-4755466)
RELA [cytosol]
(R-HSA-168172)
RELA [nucleoplasm]
(R-HSA-177676)
0.463
2
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text