MECP2 regulates transcription factors

Stable Identifier
R-HSA-9022707
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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MECP2 regulates transcription of several transcription factors involved in functioning of the nervous system, such as CREB1, MEF2C, RBFOX1 (Chahrour et al. 2008) and PPARG (Mann et al. 2010, Joss Moore et al. 2011).
Literature References
PubMed ID Title Journal Year
21425435 IUGR differentially alters MeCP2 expression and H3K9Me3 of the PPARĪ³ gene in male and female rat lungs during alveolarization

McKnight, RA, Lane, RH, Callaway, CW, Ogata, EM, Albertine, KH, Sainz, AJ, Joss-Moore, LA, Yu, X, Wang, Y

Birth Defects Res. Part A Clin. Mol. Teratol. 2011
19843474 MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis

Chu, DC, Oakley, F, Maxwell, A, Tsukamoto, H, Zhu, NL, Mann, J, Mann, DA

Gastroenterology 2010
18511691 MeCP2, a key contributor to neurological disease, activates and represses transcription

Qin, J, Jung, SY, Wong, ST, Zoghbi, HY, Shaw, C, Chahrour, M, Zhou, X

Science 2008
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