DPP4(39-766) hydrolyzes Glucose-dependent Insulinotropic Polypeptide (GIP)

Stable Identifier
R-HSA-9023626
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Dipeptidyl Peptidase IV (DPP4) cleaves 2 amino acids from the N-terminus of GIP, inactivating it. DPP4 determines the half life of GIP in the bloodstream. It is unknown if the soluble form of DPP4, the membrane-bound form, or both catalyze the cleavage of GIP.

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
serine-type endopeptidase activity of DPP4(39-766) [extracellular region]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created
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