NCOA1 recruits EP300 to TGFA promoter

Stable Identifier
R-HSA-9023884
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Estrogen-dependent interaction between NCOA1 and EP300 recruits EP300 to the TGFA promoter (Halachmi et al, 1994; Cavaillès et al, 1994; Harnstein et al, 2001). NCOA1 and EP300 contribute to active chromatin structures through their coactivator and histone acetyltransferase activity (reviewed in Xu et al, 2007; Arnal et al, 2017).

Literature References
PubMed ID Title Journal Year
7937828 Interaction of proteins with transcriptionally active estrogen receptors

Cavaillès, V, Dauvois, S, Danielian, PS, Parker, MG

Proc. Natl. Acad. Sci. U.S.A. 1994
28539435 Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications

Arnal, JF, Lenfant, F, Métivier, R, Flouriot, G, Henrion, D, Adlanmerini, M, Fontaine, C, Gourdy, P, Chambon, P, Katzenellenbogen, B, Katzenellenbogen, J

Physiol. Rev. 2017
8197458 Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription

Halachmi, S, Marden, E, Martin, G, MacKay, H, Abbondanza, C, Brown, M

Science 1994
14631847 Acetylation and methylation in nuclear receptor gene activation

Xu, W, Cho, H, Evans, RM

Meth. Enzymol. 2003
8876171 p300 is a component of an estrogen receptor coactivator complex

Hanstein, B, Eckner, R, DiRenzo, J, Halachmi, S, Liu, H, Searcy, B, Kurokawa, R, Brown, M

Proc. Natl. Acad. Sci. U.S.A. 1996
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