GGT hydrolyses RCTR1 to RCTR2

Stable Identifier
R-HSA-9026927
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Presumably following a similar synthesis route to protectin conjugate in tissue regeneration 2 (PCTR2), resolvin conjugate in tissue regeneration 1 (RCTR1) could be hydrolysed to RCTR2 (8-cysteinylglycinyl, 7,17-dihydroxy-docosahexaenoic acid) by the actions of a glutathione transferase (GGT) (Dalli et al. 2015).
Literature References
PubMed ID Title Journal Year
25713027 Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways

Norris, PC, Serhan, CN, Colas, RA, Ramon, S, Dalli, J

FASEB J. 2015
Participants
Participates
Catalyst Activity

glutathione hydrolase activity of GGT [cytosol]

Authored
Reviewed
Created
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