Sulfido conjugates translocate from cytosol to extracellular region

Stable Identifier
R-HSA-9031856
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
cytosol, extracellular region
ReviewStatus
5/5
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Sulfido conjugates translocate from cytosol to extracellular region
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To produce their pro-resolving effects, DHA-derived sulfido conjugates (MCTR1-3, PCTR1-3 and RCTR1-3) are released into the exudate of local inflammation sites (Dalli et al. 2015, 2016). The mechanism of translocation is unknown.
Literature References
PubMed ID Title Journal Year
27791009 Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages

Riley, IR, Serhan, CN, Rodriguez, AR, Petasis, NA, Chiang, N, Spur, BW, Vlasakov, I, Dalli, J

Proc. Natl. Acad. Sci. U.S.A. 2016
25713027 Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways

Norris, PC, Serhan, CN, Colas, RA, Ramon, S, Dalli, J

FASEB J. 2015
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Authored
Jassal, B  (2017-12-04)
Reviewed
Hansen, TV  (2018-02-21)
Created
Jassal, B  (2017-12-04)
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