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PEX26 [peroxisomal membrane]
Stable Identifier
R-HSA-9033092
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
peroxisomal membrane
Synonyms
Peroxisome assembly protein 26, PEX26_HUMAN
Locations in the PathwayBrowser
Expand all
Protein localization (Homo sapiens)
Class I peroxisomal membrane protein import (Homo sapiens)
PEX3:PEX19:class I PMP dissociates (Homo sapiens)
Class I Peroxisomal Membrane Proteins [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
Peroxisomal protein import (Homo sapiens)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12 (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5L:PEX7:PEX13:PEX14:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX13:PEX14 binds PEX1:PEX6:PEX26 and ZFAND6 (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
PEX2:PEX10:PEX12:Ub:PEX5S,L:PEX1:PEX6:PEX26:ZFAND6 [peroxisomal membrane] (Homo sapiens)
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
PEX26 [peroxisomal membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q7Z412 PEX26
Gene Names
PEX26
Chain
chain:1-305
Reference Genes
BioGPS Gene:55670 PEX26
COSMIC (genes):PEX26 PEX26
CTD Gene:55670 PEX26
dbSNP Gene:55670 PEX26
ENSEMBL:ENSG00000215193 PEX26
HGNC:22965 PEX26
KEGG Gene (Homo sapiens):55670 PEX26
Monarch:55670 PEX26
NCBI Gene:55670 PEX26
OMIM:608666 PEX26
UCSC:Q7Z412 PEX26
Reference Transcript
RefSeq:NM_017929.5 PEX26
RefSeq:NM_001127649.2 PEX26
RefSeq:NM_001199319.1 PEX26
Other Identifiers
0002650110
11730953_a_at
11730954_a_at
11736832_a_at
16926922
16926932
219180_s_at
235098_at
240123_at
3936446
3936447
3936448
3936449
3936450
3936451
3936452
3936455
3936456
3936457
3936459
3936460
3936462
3936463
3936464
3936465
3936466
3936468
3936469
3936470
3936471
3936472
3936473
3936474
3936475
3936476
3936477
3936478
3936479
3936500
3936502
3936503
3936505
3936507
3936509
3936511
3936513
3936514
3936516
3936517
3936518
3936519
3936520
3936521
3936532
3936534
3936536
3936538
3936540
3936541
3936543
3936545
45708_i_at
45709_r_at
50052_i_at
50055_r_at
55670
60592_at
60671_at
62200_at
76507_at
8071136
86037_at
A_14_P108335
A_14_P132927
A_24_P142973
A_33_P3262452
A_33_P3412519
GE494100
GE55595
GE838500
GE868789
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005737
GO:0005777
GO:0005778
GO:0005779
GO:0006605
GO:0006625
GO:0006810
GO:0008022
GO:0008150
GO:0015031
GO:0016020
GO:0016021
GO:0016558
GO:0019899
GO:0043226
GO:0044877
GO:0045046
GO:0051117
GO:0055085
HMNXSV003006694
Hs.127953.0.S1_3p_at
Hs.177169.0.A1_3p_at
Hs.5420.0.S1_3p_a_at
ILMN_1738065
ILMN_1770643
ILMN_2130409
PH_hs_0013638
PH_hs_0026013
TC22000947.hg
TC22001451.hg
Participates
as a member of
Class I Peroxisomal Membrane Proteins [peroxisomal membrane] (Homo sapiens)
as a component of
PEX1:PEX6:PEX26 [peroxisomal membrane] (Homo sapiens)
Other forms of this molecule
PEX26 [cytosol]
Inferred To
Ghost homologue of PEX26 [peroxisomal membrane]
(Caenorhabditis elegans)
Ghost homologue of PEX26 [peroxisomal membrane]
(Dictyostelium discoideum)
Ghost homologue of PEX26 [peroxisomal membrane]
(Drosophila melanogaster)
Ghost homologue of PEX26 [peroxisomal membrane]
(Saccharomyces cerevisiae)
Ghost homologue of PEX26 [peroxisomal membrane]
(Schizosaccharomyces pombe)
Ghost homologue of PEX26 [peroxisomal membrane]
(Sus scrofa)
pex26 [peroxisomal membrane]
(Danio rerio)
Pex26 [peroxisomal membrane]
(Mus musculus)
Pex26 [peroxisomal membrane]
(Rattus norvegicus)
PEX26 [peroxisomal membrane]
(Canis familiaris)
PEX26 [peroxisomal membrane]
(Gallus gallus)
Cross References
RefSeq
NP_001121121.1
,
NP_060399.1
,
NP_001186248.1
OpenTargets
ENSG00000215193
GeneCards
Q7Z412
HPA
ENSG00000215193-PEX26
Ensembl
ENST00000428061
,
ENSP00000382648
,
ENST00000329627
,
ENSP00000331106
,
ENSP00000412441
,
ENST00000399744
,
ENSG00000215193
PRO
Q7Z412
Orphanet
16644
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P40855 PEX19
1
PEX19 [cytosol]
(R-HSA-3009036)
0.683
9
UniProt:A0AVK6 E2F8
1
E2F8 [nucleoplasm]
(R-HSA-8952990)
0.556
3
UniProt:Q96LC9 BMF
3
p-BMF(1-89) [cytosol]
(R-HSA-140529)
BMF [plasma membrane]
(R-HSA-140209)
p-BMF [mitochondrial outer membrane]
(R-HSA-3145026)
0.556
3
UniProt:Q9UER7 DAXX
13
DAXX L98Vfs*13 [nucleoplasm]
(R-HSA-9673102)
SUMO1-K630,K631-DAXX [nucleoplasm]
(R-HSA-4086086)
DAXX R48Vfs*93 [nucleoplasm]
(R-HSA-9673103)
DAXX C74* [nucleoplasm]
(R-HSA-9673096)
DAXX S138* [nucleoplasm]
(R-HSA-9673081)
DAXX H26Tfs*118 [nucleoplasm]
(R-HSA-9673114)
DAXX E104* [nucleoplasm]
(R-HSA-9673078)
DAXX E72Nfs*72 [nucleoplasm]
(R-HSA-9673110)
DAXX C106* [nucleoplasm]
(R-HSA-9673079)
DAXX A103Sfs*40 [nucleoplasm]
(R-HSA-9673121)
DAXX K56* [nucleoplasm]
(R-HSA-9673089)
DAXX A36Qfs*108 [nucleoplasm]
(R-HSA-9673105)
DAXX [nucleoplasm]
(R-HSA-3222068)
0.556
3
UniProt:Q969S8 HDAC10
1
HDAC10 [nucleoplasm]
(R-HSA-351579)
0.556
3
UniProt:O15392 BIRC5
3
BIRC5 [nucleoplasm]
(R-HSA-4655344)
ub-BIRC5 [cytosol]
(R-HSA-8955933)
BIRC5 [cytosol]
(R-HSA-50851)
0.556
3
UniProt:P04637 TP53
27
TP53 [cytosol]
(R-HSA-8869337)
Unfolded TP53 [cytosol]
(R-HSA-6813797)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
SUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
Me1-K372,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805719)
Me2-K373-TP53 [nucleoplasm]
(R-HSA-6805759)
Me-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222124)
MeK-370,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-3222226)
p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm]
(R-HSA-6804378)
Me2K-370,382-TP53 [nucleoplasm]
(R-HSA-3222242)
p-S15,S33,S46-TP53 [nucleoplasm]
(R-HSA-6805268)
p-S15,S392-TP53 [nucleoplasm]
(R-HSA-3222015)
p-T55-TP53 [nucleoplasm]
(R-HSA-6805400)
p-S15,S20,S392-TP53 [nucleoplasm]
(R-HSA-6805053)
p-S15,S20,S269,T284-TP53 [nucleoplasm]
(R-HSA-6805133)
p-S315-TP53 [nucleoplasm]
(R-HSA-6805106)
Ac-K120,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805656)
Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6805631)
Ac-K382,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-5628868)
p-S37-TP53 [nucleoplasm]
(R-HSA-3239022)
PolyUb,p-S15,S20-TP53 [nucleoplasm]
(R-HSA-6804446)
p-S15,S20,S46-TP53 [nucleoplasm]
(R-HSA-6798369)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6793679)
PolyUb-TP53 [cytosol]
(R-HSA-6793681)
p-S15,S20-TP53 [nucleoplasm]
(R-HSA-69683)
p-S15-TP53 [nucleoplasm]
(R-HSA-69507)
TP53 [nucleoplasm]
(R-HSA-69488)
0.556
3
UniProt:Q9UMX1 SUFU
3
SUFU [cytosol]
(R-HSA-445455)
SUFU [ciliary base]
(R-HSA-5610424)
SUFU [ciliary tip]
(R-HSA-5610426)
0.508
2
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