Reactome | CAT [cytosol]

CAT [cytosol]

Stable Identifier

R-HSA-9033141

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Catalase ecNumber1.11.1.6/ecNumber, CATA_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P04040 CAT

Gene Names

CAT

Chain

initiator methionine:, chain:2-527

Reference Genes

BioGPS Gene:847 CAT

COSMIC (genes):CAT CAT

CTD Gene:847 CAT

dbSNP Gene:847 CAT

ENSEMBL:ENSG00000121691 CAT

HGNC:1516 CAT

KEGG:hsa:847 CAT

Monarch:847 CAT

NCBI Gene:847 CAT

OMIM:115500 CAT

UCSC:P04040 CAT

Reference Transcript

RefSeq:NM_001752.3 CAT

Other Identifiers

11732147_a_at

11732148_at

16723546

201432_PM_at

201432_at

211922_PM_s_at

211922_s_at

3326401

3326402

3326408

3326409

3326410

3326411

3326412

3326414

3326416

3326417

3326419

3326420

3326421

3326422

3326423

3326425

3326426

3326427

3326428

3326429

3326430

3326431

3326432

3326433

3326434

3326437

3326439

3326442

3326443

3326444

37009_at

7939298

847

A_23_P105138

A_24_P925191

GE61602

GE86486

GO:0000302

GO:0001649

GO:0001657

GO:0001666

GO:0001822

GO:0003824

GO:0004046

GO:0004096

GO:0004601

GO:0005576

GO:0005615

GO:0005737

GO:0005739

GO:0005777

GO:0005778

GO:0005782

GO:0005829

GO:0005925

GO:0006091

GO:0006629

GO:0006641

GO:0006979

GO:0008203

GO:0009060

GO:0009410

GO:0009411

GO:0009636

GO:0009642

GO:0009650

GO:0010193

GO:0010288

GO:0014823

GO:0014854

GO:0016020

GO:0016209

GO:0016491

GO:0016684

GO:0016787

GO:0019899

GO:0020027

GO:0020037

GO:0030154

GO:0032355

GO:0032868

GO:0032991

GO:0033189

GO:0033197

GO:0033591

GO:0034774

GO:0042542

GO:0042744

GO:0042802

GO:0042803

GO:0043066

GO:0043226

GO:0043231

GO:0045471

GO:0046686

GO:0046872

GO:0048856

GO:0050661

GO:0051781

GO:0051897

GO:0055093

GO:0061692

GO:0062151

GO:0070062

GO:0070542

GO:0071363

GO:0072722

GO:0080184

GO:0098754

GO:0098869

GO:1904813

HMNXSV003031029

Hs.287482.0.S1_3p_at

ILMN_1651705

ILMN_2151739

PH_hs_0018945

TC11000327.hg

X04085_rna1_at

g13562131_3p_s_at

g4557013_3p_at

Participates

as a member of

Cargo proteins containing PTS1 [cytosol] (Homo sapiens)

as an output of

Other forms of this molecule

CAT [peroxisomal matrix]

CAT [ficolin-1-rich granule lumen]

CAT [extracellular region]

CAT [secretory granule lumen]

Inferred To

CAT [cytosol] (Bos taurus)

CAT [cytosol] (Caenorhabditis elegans)

CAT [cytosol] (Canis familiaris)

CAT [cytosol] (Dictyostelium discoideum)

CAT [cytosol] (Drosophila melanogaster)

CAT [cytosol] (Gallus gallus)

CAT [cytosol] (Rattus norvegicus)

CAT [cytosol] (Saccharomyces cerevisiae)

CAT [cytosol] (Schizosaccharomyces pombe)

CAT [cytosol] (Sus scrofa)

CAT [cytosol] (Xenopus tropicalis)

Cat [cytosol] (Mus musculus)

Cross References

Guide to Pharmacology - Targets

2979

ENSEMBL

ENST00000241052, ENSP00000241052

OpenTargets

ENSG00000121691

HPA

ENSG00000121691-CAT

PRO

P04040

Pharos - Targets

P04040

GlyGen

P04040

Orphanet

CAT

HMDB Protein

HMDBP01582

PDB

1F4J, 1DGB, 8PVD, 7VD9, 8HID, 7P8W, 8SGV, 1QQW, 1DGH, 1DGF, 1DGG, 8EL9

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04040 CAT	5	CAT [cytosol] (R-HSA-9033141) CAT [peroxisomal matrix] (R-HSA-51417) CAT [ficolin-1-rich granule lumen] (R-HSA-6801279) CAT [extracellular region] (R-HSA-6806458) CAT [secretory granule lumen] (R-HSA-6801311)	0.594	5
UniProt:Q2T9J0 TYSND1	4	TYSND1(111-566) [peroxisomal matrix] (R-HSA-9033589) TYSND1(1-110) [peroxisomal matrix] (R-HSA-9033587) TYSND1 [peroxisomal matrix] (R-HSA-8933309) TYSND1 [cytosol] (R-HSA-9033586)	0.548	4
UniProt:Q06124 PTPN11	4	p-Y542,Y580-PTPN11 [cytosol] (R-HSA-162573) PTPN11 [cytosol] (R-HSA-162563) PTPN11 [nucleoplasm] (R-HSA-8937745) p-Y542-PTPN11 [cytosol] (R-HSA-1369081)	0.544	3
UniProt:P51532 SMARCA4	1	SMARCA4 [nucleoplasm] (R-HSA-201686)	0.483	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	6