NTRK2 promotes TIAM1 phosphorylation

Stable Identifier
R-HSA-9033284
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
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Upon binding to NTRK2 (TRKB), TIAM1 is phosphorylated at tyrosine residue Y829, presumably by NTRK2, but this has not been shown directly (Lai et al. 2012).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of BDNF:p-5Y,S479-NTRK2 homodimer:TIAM1 [plasma membrane]
Physical Entity
Activity
Inferred From
Authored
Reviewed
Created