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IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
Stable Identifier
R-HSA-909711
Type
Complex
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
Phosphorylation of STAT1 (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Interferon alpha/beta signaling (Homo sapiens)
Phosphorylation of STAT1 (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Homo sapiens)
Regulation of IFNA/IFNB signaling (Homo sapiens)
Dephosphorylation of STAT1 by SHP2 (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Homo sapiens)
Release of p-STAT2:p-STAT1 dimer (Homo sapiens)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Homo sapiens)
Participants
components
IFN alpha/beta (IFNA/B) [extracellular region]
(Homo sapiens)
IFNAR2:p-JAK1:STAT2 [plasma membrane]
(Homo sapiens)
p-STAT2:p-STAT1:p-IFNAR1:p-TYK2 [plasma membrane]
(Homo sapiens)
Participates
as an input of
Dephosphorylation of STAT1 by SHP2 (Homo sapiens)
Release of p-STAT2:p-STAT1 dimer (Homo sapiens)
as an output of
Phosphorylation of STAT1 (Homo sapiens)
Inferred To
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
(Bos taurus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
(Canis familiaris)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
(Gallus gallus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
(Mus musculus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
(Rattus norvegicus)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
(Sus scrofa)
IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane]
(Xenopus tropicalis)
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