Synapsis

Stable Identifier
R-HSA-912505
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
Synonyms
Formation of Central Elements of the Synaptonemal Complex
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Initiation of recombination precedes and is required for synapsis (Roig et al. 2004). The synaptonemal complex forms when transverse filaments of SYCP1 link axial/lateral elements of sister chromatids to a central element comprising SYCE1, SYCE2, and other proteins (Tarsounas et al. 1997). The order of assembly is unknown.

Literature References
PubMed ID Title Journal Year
9285814 Protein-protein interactions in the synaptonemal complex

Tarsounas, M, Pearlman, RE, Gasser, PJ, Park, MS, Moens, PB

Mol Biol Cell 1997
15235794 Female-specific features of recombinational double-stranded DNA repair in relation to synapsis and telomere dynamics in human oocytes

Roig, I, Liebe, B, Egozcue, J, Cabero, L, Garcia, M, Scherthan, H

Chromosoma 2004
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