Reactome | ATP6V1E1 [cytosol]

ATP6V1E1 [cytosol]

Stable Identifier

R-HSA-912606

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser for interactor UniProt:O75348 ATP6V1G1

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External Reference Information

External Reference

UniProt:P36543 ATP6V1E1

Gene Names

ATP6V1E1, ATP6E, ATP6E2

Chain

initiator methionine:, chain:2-226

Reference Genes

BioGPS Gene:529 ATP6V1E1

COSMIC (genes):ATP6V1E1 ATP6V1E1

CTD Gene:529 ATP6V1E1

dbSNP Gene:529 ATP6V1E1

ENSEMBL:ENSG00000131100 ATP6V1E1

HGNC:857 ATP6V1E1

KEGG:hsa:529 ATP6V1E1

Monarch:529 ATP6V1E1

NCBI Gene:529 ATP6V1E1

OMIM:108746 ATP6V1E1

UCSC:P36543 ATP6V1E1

Reference Transcript

Other Identifiers

11717011_a_at

11741370_a_at

16931990

208678_PM_at

208678_at

37367_at

3951888

3951889

3951890

3951891

3951892

3951893

3951894

3951895

3951896

3951897

3951898

3951901

3951902

3951903

3951904

3951905

3951907

3951908

529

8074251

A_23_P143551

GE60017

GO:0000221

GO:0005215

GO:0005515

GO:0005737

GO:0005765

GO:0005768

GO:0005829

GO:0005886

GO:0005902

GO:0006811

GO:0016241

GO:0016324

GO:0016469

GO:0030665

GO:0030672

GO:0031410

GO:0033178

GO:0043226

GO:0045202

GO:0046961

GO:0051117

GO:0055085

GO:0070062

GO:0097401

GO:0140657

GO:1902600

HMNXSV003035320

ILMN_1798485

ILMN_2339779

PH_hs_0004491

PH_hs_0035464

TC22000474.hg

X76228_at

g13325247_3p_at

Participates

as an output of

MITF-M-dependent ATP6V1E1 gene expression (Homo sapiens)

as a member of

ATP6V1E [cytosol] (Homo sapiens)

Inferred To

VMA4 [cytosol] (Saccharomyces cerevisiae)

ATP6V1E1 [cytosol] (Bos taurus)

ATP6V1E1 [cytosol] (Canis familiaris)

ATP6V1E1 [cytosol] (Gallus gallus)

ATP6V1E1 [cytosol] (Plasmodium falciparum)

ATP6V1E1 [cytosol] (Sus scrofa)

vma4 [cytosol] (Schizosaccharomyces pombe)

atp6v1e1 [cytosol] (Xenopus tropicalis)

vatE [cytosol] (Dictyostelium discoideum)

atp6v1e1b [cytosol] (Danio rerio)

vha-8 [cytosol] (Caenorhabditis elegans)

Atp6v1e1 [cytosol] (Mus musculus)

Atp6v1e1 [cytosol] (Rattus norvegicus)

Vha26 [cytosol] (Drosophila melanogaster)

Cross References

RefSeq

NP_001687.1, NP_001034455.1, NP_001034456.1

Guide to Pharmacology - Targets

816

ENSEMBL

ENSP00000253413, ENSP00000382696, ENSG00000131100, ENST00000253413, ENST00000399798, ENSP00000382694, ENST00000399796

OpenTargets

ENSG00000131100

GeneCards

ATP6V1E1

HPA

ENSG00000131100-ATP6V1E1

PRO

P36543

Pharos - Targets

P36543

GlyGen

P36543

HMDB Protein

HMDBP09534

PDB

7UNF, 6WM2, 6WM3, 7U4T, 6WLZ, 6WM4

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75348 ATP6V1G1	1	ATP6V1G1 [cytosol] (R-HSA-912578)	0.547	3
UniProt:O75787 ATP6AP2	3	ATP6AP2 [plasma membrane] (R-HSA-2022356) ATP6AP2 [tertiary granule membrane] (R-HSA-6799717) ATP6AP2 [ficolin-1-rich granule membrane] (R-HSA-6800921)	0.527	2
UniProt:P38606 ATP6V1A	1	ATP6V1A [cytosol] (R-HSA-912602)	0.527	3