Cbl and Vav interact in thymocytes and peripheral T cells (Marengere et al. 1997). Cbl phosphorylated at Y700 binds Vav1 in 293T cells, leading to Vav ubiquitinylation and proteolytic degradation.
Miura-Shimura, Y, Duan, L, Rao, NL, Reddi, AL, Shimura, H, Rottapel, R, Druker, BJ, Tsygankov, A, Band, V, Band, H
Marengère, LE, Mirtsos, C, Kozieradzki, I, Veillette, A, Mak, TW, Penninger, JM
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