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SHP2 can recruit GRB2

Stable Identifier
R-HSA-914022
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

SHP2 can associate with GRB2 (Stein-Gerlach et al. 1995). IL-3 induces the phosphorylation of SHP2 and its association with GRB2 (Welham et al. 1994). SHP2 may act as a scaffold protein to recruit other signaling molecules, e.g. SHP2 was reported to link GRB2 to the receptor tyrosine kinase c-kit (Tauchi et al. 1994).

Participants
Participant Of
Inferred From