Reactome | CHMP7 [cytosol]

CHMP7 [cytosol]

Stable Identifier

R-HSA-917703

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Charged multivesicular body protein 7, CHMP7_HUMAN

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WUX9 CHMP7

Gene Names

CHMP7

Chain

chain:1-453

Reference Genes

BioGPS Gene:91782 CHMP7

COSMIC (genes):CHMP7 CHMP7

CTD Gene:91782 CHMP7

dbSNP Gene:91782 CHMP7

ENSEMBL:ENSG00000147457 CHMP7

HGNC:28439 CHMP7

KEGG:hsa:91782 CHMP7

Monarch:91782 CHMP7

NCBI Gene:91782 CHMP7

OMIM:611130 CHMP7

UCSC:Q8WUX9 CHMP7

Reference Transcript

RefSeq:NM_152272.4 CHMP7

Other Identifiers

11716147_s_at

11750037_a_at

17066845

212313_PM_at

212313_at

2993694

3089854

3089855

3089856

3089857

3089858

3089859

3089860

3089863

3089864

3089865

3089866

3089867

3089870

3089871

3089872

3089873

3089874

3089875

3089876

3089877

3089878

3089879

3089880

3089881

3089882

3089883

3089884

3089885

3089886

34871_at

7894787

8145259

91782

A_23_P303203

A_32_P70220

GE87421

GO:0000421

GO:0000776

GO:0000785

GO:0000815

GO:0001778

GO:0005515

GO:0005634

GO:0005635

GO:0005643

GO:0005654

GO:0005737

GO:0005765

GO:0005768

GO:0005771

GO:0005828

GO:0005829

GO:0005886

GO:0006900

GO:0006914

GO:0006997

GO:0007034

GO:0007080

GO:0009898

GO:0010458

GO:0015031

GO:0016192

GO:0030496

GO:0031410

GO:0031468

GO:0032511

GO:0032585

GO:0036258

GO:0039702

GO:0043162

GO:0043226

GO:0045324

GO:0046761

GO:0051469

GO:0061024

GO:0061763

GO:0061952

GO:0071168

GO:0071985

GO:0090148

GO:0097352

GO:1901673

GO:1902774

GO:1904903

GO:1904930

HMNXSV003031815

Hs.5019.0.S1_3p_at

ILMN_1795933

PH_hs_0000516

TC08000184.hg

Participates

as an output of

as an input of

CHMP7 binds LEMD2 (Homo sapiens)

as a component of

Other forms of this molecule

CHMP7 [endosome membrane]

Inferred To

CHMP7 [cytosol] (Bos taurus)

CHMP7 [cytosol] (Canis familiaris)

CHMP7 [cytosol] (Gallus gallus)

CHMP7 [cytosol] (Saccharomyces cerevisiae)

CHMP7 [cytosol] (Sus scrofa)

Homologues of CHMP7 [cytosol] (Dictyostelium discoideum)

Homologues of CHMP7 [cytosol] (Saccharomyces cerevisiae)

Ghost homologue of CHMP7 [cytosol] (Caenorhabditis elegans)

chmp6 [cytosol] (Dictyostelium discoideum)

vps20 [cytosol] (Schizosaccharomyces pombe)

BcDNA.GH08385 [cytosol] (Drosophila melanogaster)

chmp7 [cytosol] (Danio rerio)

chmp7 [cytosol] (Dictyostelium discoideum)

chmp7 [cytosol] (Xenopus tropicalis)

Chmp7 [cytosol] (Mus musculus)

Chmp7 [cytosol] (Rattus norvegicus)

VPS20 [cytosol] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_689485.1

ENSEMBL

ENSP00000380794, ENST00000313219, ENSP00000427948, ENST00000397677, ENST00000519503, ENSP00000324491

OpenTargets

ENSG00000147457

HPA

ENSG00000147457-CHMP7

PRO

Q8WUX9

Pharos - Targets

Q8WUX9

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01112 HRAS	20	S-Farn-Me-2xPalmS HRAS [plasma membrane] (R-HSA-9647912) proHRAS [cytosol] (R-HSA-9647765) S-Farn-proHRAS [endoplasmic reticulum membrane] (R-HSA-9647918) S-Farn-HRAS [endoplasmic reticulum membrane] (R-HSA-9647788) S-Farn-Me HRAS [endoplasmic reticulum membrane] (R-HSA-9647796) S-Farn-Me PalmS HRAS [Golgi membrane] (R-HSA-9647896) S-Farn-Me HRAS [plasma membrane] (R-HSA-9665052) HRAS [plasma membrane] (R-HSA-62717) HRAS G12C [plasma membrane] (R-HSA-9656561) HRAS G12D [plasma membrane] (R-HSA-9656564) HRAS K117N [plasma membrane] (R-HSA-9656603) HRAS G13S [plasma membrane] (R-HSA-9656574) HRAS G13D [plasma membrane] (R-HSA-9656572) HRAS G13V [plasma membrane] (R-HSA-9656579) HRAS K117R [plasma membrane] (R-HSA-9656010) HRAS G13C [plasma membrane] (R-HSA-9656008) HRAS T58I [plasma membrane] (R-HSA-9656014) HRAS G12S [plasma membrane] (R-HSA-6802343) HRAS G12V [plasma membrane] (R-HSA-6802350) HRAS G13R [plasma membrane] (R-HSA-6802368)	0.659	4
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) p-6Y-FGFR3 A391E [plasma membrane] (R-HSA-2065835) p-6Y-FGFR3 K650T [plasma membrane] (R-HSA-2032966) p-6Y-FGFR3 G382D [plasma membrane] (R-HSA-2032950) p-6Y-FGFR3 G380R [plasma membrane] (R-HSA-2032946) p-6Y-FGFR3 K650M [plasma membrane] (R-HSA-2032959)	0.556	3
UniProt:P06396 GSN	7	GSN [cytosol] (R-HSA-350275) GSN(28-403) [cytosol] (R-HSA-201618) GSN(404-782) [cytosol] (R-HSA-350272) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(200-270) [extracellular region] (R-HSA-976940)	0.556	3
UniProt:Q7Z699 SPRED1	2	SPRED1 [plasma membrane] (R-HSA-5658225) SPRED1 [cytosol] (R-HSA-5654207)	0.556	3
UniProt:A0A6Q8PF08 A0A6Q8PF08			0.556	3
UniProt:G5E9A7 G5E9A7			0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [plasma membrane] (R-HSA-419560) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189)	0.556	3
UniProt:P28329-3 P283293			0.556	3
UniProt:Q9BVL2 NUP58			0.556	3
UniProt:P62826 RAN	2	RAN [cytosol] (R-HSA-165540) RAN [nucleoplasm] (R-HSA-165528)	0.556	3
UniProt:P55212 CASP6	5	CASP6(194-293) [cytosol] (R-HSA-266128) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6 (1-293) [cytosol] (R-HSA-6798132)	0.556	3
UniProt:O14645 IDLC			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:P13473-2 P134732			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:Q0VDC6 Q0VDC6			0.556	3
UniProt:P54652 HSPA2	2	HSPA2 [cytosol] (R-HSA-3371408) HSPA2 [nucleoplasm] (R-HSA-912480)	0.556	3
UniProt:P06307 CCK	1	CCK [extracellular region] (R-HSA-388539)	0.556	3
UniProt:Q15102 PAFAH1B3	1	PAFAH1B3 [cytosol] (R-HSA-8848134)	0.553	2
UniProt:Q9H444 CHMP4B	2	CHMP4B [cytosol] (R-HSA-917708) CHMP4B [endosome membrane] (R-HSA-9631202)	0.543	3

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