Fe3+ dissociates from holoTF:TFRC dimer

Stable Identifier
R-HSA-917835
Type
Reaction [dissociation]
Species
Homo sapiens
Compartment
endosome lumen, endosome membrane
ReviewStatus
5/5
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Fe3+ dissociates from holoTF:TFRC dimer
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When endosomal pH reaches 6,0, protons replace the iron ions in the transferrin/receptor complex (Hemadi et al, 2006).
Literature References
PubMed ID Title Journal Year
16564538 The mechanism of iron release from the transferrin-receptor 1 adduct

Hémadi, M, Ha-Duong, NT, El Hage Chahine, JM

J Mol Biol 2006
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Orthologous Events
Fe3+ dissociates from holoTF:TFRC dimer (Bos taurus)
Fe3+ dissociates from holoTF:TFRC dimer (Gallus gallus)
Fe3+ dissociates from holoTF:TFRC dimer (Mus musculus)
Fe3+ dissociates from holoTF:TFRC dimer (Rattus norvegicus)
Fe3+ dissociates from holoTF:TFRC dimer (Sus scrofa)
Authored
Stephan, R  (2010-07-14)
Reviewed
D'Eustachio, P  (2010-11-05)
Created
Jassal, B  (2010-07-30)
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