Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
STEAP3 [endosome membrane]
Stable Identifier
R-HSA-917861
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Transcription of Cell Death Genes (Homo sapiens)
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release (Homo sapiens)
STEAP3 binds BNIP3L (Homo sapiens)
STEAP3 [endosome membrane] (Homo sapiens)
STEAP3:BNIP3L [mitochondrial outer membrane] (Homo sapiens)
STEAP3 [endosome membrane] (Homo sapiens)
TP53 stimulates STEAP3 expression (Homo sapiens)
STEAP3 [endosome membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Iron uptake and transport (Homo sapiens)
Transferrin endocytosis and recycling (Homo sapiens)
STEAP3-like proteins reduce Fe3+ to Fe2+ (Homo sapiens)
STEAP3-like proteins [endosome membrane] (Homo sapiens)
STEAP3 [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q658P3 STEAP3
Gene Names
STEAP3, TSAP6
Chain
chain:1-488
Reference Genes
BioGPS Gene:55240 STEAP3
COSMIC (genes):STEAP3 STEAP3
CTD Gene:55240 STEAP3
dbSNP Gene:55240 STEAP3
ENSEMBL:ENSG00000115107.20 STEAP3
HGNC:24592 STEAP3
KEGG Gene (Homo sapiens):55240 STEAP3
Monarch:55240 STEAP3
NCBI Gene:55240 STEAP3
OMIM:609671 STEAP3
UCSC:Q658P3 STEAP3
Reference Transcript
RefSeq:NM_182915.2 STEAP3
RefSeq:NM_001008410.1 STEAP3
RefSeq:XM_011511403.1 STEAP3
RefSeq:XM_006712614.3 STEAP3
RefSeq:XM_006712615.1 STEAP3
RefSeq:NM_138637.2 STEAP3
RefSeq:NM_018234.2 STEAP3
Other Identifiers
0001170546
0101770408
11722677_a_at
11722678_a_at
11752403_a_at
1554830_PM_a_at
1554830_a_at
16884956
218424_PM_s_at
218424_s_at
237212_PM_at
237212_at
2502780
2502782
2502783
2502787
2502789
2502790
2502796
2502797
2502798
2502799
2502800
2502801
2502802
2502803
2502804
2502805
2502806
2502807
2502808
2502809
2502810
43811_at
53159_at
55240
72259_at
8044793
A_23_P90601
A_24_P200000
GE55877
GE904980
GO:0005515
GO:0005622
GO:0005737
GO:0005768
GO:0005771
GO:0005886
GO:0006811
GO:0006915
GO:0007049
GO:0008823
GO:0009306
GO:0010008
GO:0012501
GO:0015677
GO:0016020
GO:0016021
GO:0016491
GO:0016723
GO:0031410
GO:0033572
GO:0043226
GO:0046872
GO:0052851
GO:0055065
GO:0055072
HMNXSV003025809
Hs.100554.0.A1_3p_at
Hs2.57655.3.A1_3p_s_at
ILMN_1746926
ILMN_1761577
ILMN_1831372
ILMN_2281089
ILMN_2383349
PH_hs_0003687
PH_hs_0005611
TC02000750.hg
g8922696_3p_a_at
Participates
as a member of
STEAP3-like proteins [endosome membrane] (Homo sapiens)
as an output of
TP53 stimulates STEAP3 expression (Homo sapiens)
as a component of
STEAP3:BNIP3L [mitochondrial outer membrane] (Homo sapiens)
as an input of
STEAP3 binds BNIP3L (Homo sapiens)
Other forms of this molecule
STEAP3 [plasma membrane]
Inferred To
STEAP3 [endosome membrane]
(Bos taurus)
STEAP3 [endosome membrane]
(Canis familiaris)
STEAP3 [endosome membrane]
(Gallus gallus)
STEAP3 [endosome membrane]
(Mus musculus)
STEAP3 [endosome membrane]
(Rattus norvegicus)
STEAP3 [endosome membrane]
(Sus scrofa)
steap3 [endosome membrane]
(Xenopus tropicalis)
si:ch73-250a16.3 [endosome membrane]
(Danio rerio)
Cross References
RefSeq
NP_060704.2
,
XP_011509705.1
,
XP_006712678.1
,
NP_878919.2
,
XP_006712677.1
,
NP_619543.2
,
NP_001008410.1
OpenTargets
ENSG00000115107
GeneCards
Q658P3
HPA
ENSG00000115107-STEAP3
Ensembl
ENST00000393110
,
ENSP00000376819
,
ENSP00000376818
,
ENSG00000115107
,
ENSP00000376822
,
ENST00000393107
,
ENST00000393106
PRO
Q658P3
Pharos - Targets
Q658P3
Orphanet
22232
PDB
2VNS
,
2VQ3
HMDB Protein
HMDBP08258
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q8NDW8 TT21A
0.534
2
UniProt:P0DTD8 NS7B
0.527
2
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text