SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+

Stable Identifier
R-HSA-917891
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
Oxidation of Fe2+ by ceruloplasmin
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In tissues other than the duodenum, ceruloplasmin (CP), in complex with SLC40A1 and 6 copper ions, oxidises ferrous iron (Fe2+) to ferric iron (Fe3+) after it is exported from the cell (Sato et al. 1990).

Literature References
PubMed ID Title Journal Year
2154449 Detection of multiple forms of human ceruloplasmin. A novel Mr 200,000 form

Sato, M, Schilsky, ML, Stockert, RJ, Morell, AG, Sternlieb, I

J Biol Chem 1990
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ferroxidase activity of SLC40A1:CP:6Cu2+ [plasma membrane]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created