Interaction of MEKK1 with TRAF6

Stable Identifier
R-HSA-933528
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Influenza A virus, Human respiratory syncytial virus A, Rotavirus, Hepatitis C Virus, Measles virus
Compartment
cytosol, mitochondrial outer membrane
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Interaction of MEKK1 with TRAF6
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
TRAF6 requires MEKK1 (MAP3K1) to activate NF-kB and MEKK1 may interact with TRAF6, which in turn contributes to the activation of IKK and MAPKK, leading to the activation of NF-kB and AP-1. (Yoshida et al)
Participants
Input
Output
Participates
as an event of
Inferred From
Interaction of MEKK1 with TRAF6 (Mus musculus)
Orthologous Events
MEKK1 binds TRAF6 (Gallus gallus)
Authored
Garapati, P V  (2010-08-02)
Reviewed
Akira, S  (2010-10-30)
Kawai, T  (2010-10-30)
Created
Garapati, P V  (2010-08-16)
Cite Us!