p-S112,S121-SPRY2 [plasma membrane]

Stable Identifier
R-HSA-934595
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
S112/S121-phospho Sprouty 2, hSpry2-phosphoS112/S121
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:O43597 SPRY2
Gene Names
SPRY2
Chain
chain:1-315
Reference Genes
BioGPS Gene:10253 SPRY2
COSMIC (genes):SPRY2 SPRY2
CTD Gene:10253 SPRY2
dbSNP Gene:10253 SPRY2
ENSEMBL:ENSG00000136158 SPRY2
HGNC:11270 SPRY2
KEGG Gene (Homo sapiens):10253 SPRY2
Monarch:10253 SPRY2
NCBI Gene:10253 SPRY2
OMIM:602466 SPRY2
UCSC:O43597 SPRY2
Reference Transcript
Other Identifiers
0006040164
10253
11753988_a_at
16780069
204011_at
33700_at
3519323
3519324
3519325
3519326
3519327
3519328
3519330
3519331
3519332
37205
3BUM
3OB1
42198
5HKY
5HKZ
5HL0
7972217
A_23_P128698
AAC04258
AAH15745
AF039843
AK313810
AL354668
AL713749
BAG36546
BC015745
CAB037205
CAD28524
CCDS9463
ENSG00000136158
ENSP00000366306
ENSP00000366308
ENST00000377102
ENST00000377102.5
ENST00000377104
ENST00000377104.3
EntrezGene:10253
EntrezGene:SPRY2
g5032114_3p_at
GE54345
GO:0000132
GO:0000278
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005737
GO:0005829
GO:0005856
GO:0005874
GO:0005886
GO:0006464
GO:0007010
GO:0007049
GO:0007165
GO:0007275
GO:0007605
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0009790
GO:0009966
GO:0010628
GO:0010801
GO:0015630
GO:0016020
GO:0016525
GO:0019899
GO:0019901
GO:0030154
GO:0030234
GO:0030291
GO:0030324
GO:0030335
GO:0031345
GO:0032587
GO:0033138
GO:0034260
GO:0035924
GO:0040007
GO:0040011
GO:0040037
GO:0042059
GO:0042127
GO:0042472
GO:0042995
GO:0043066
GO:0043226
GO:0043407
GO:0043539
GO:0045165
GO:0045595
GO:0046580
GO:0048646
GO:0048754
GO:0048856
GO:0048870
GO:0050877
GO:0051387
GO:0051897
GO:0060425
GO:0060437
GO:0060449
GO:0060541
GO:0070373
GO:0070374
GO:0071902
GO:1900747
GO:1990830
HGNC:11270
HPA042198
ILMN_1760820
ILMN_2089329
IPR007875
IPR030780
MIM:602466
MIM:616818
NM_001318536
NM_001318537
NM_001318538
NM_005842
NP_001305465
NP_001305466
NP_001305467
NP_005833
PF05210
PH_hs_0001652
SPRY2
SPRY2-201
SPRY2-202
TC13000763.hg
UPI0000001301
Participant Of
hasComponent
Other forms of this molecule
p-Y55,Y227-SPRY2 [plasma membrane]
p-Y55,Y227-SPRY2 [plasma membrane]
SPRY2 [plasma membrane]
SPRY2 [cytosol]
p-S112,S115-SPRY2 [cytosol]
p-S111,S120-SPRY2 [cytosol]
p-Y55-SPRY2 [cytosol]
Inferred To
phospho-p-S112,S121-SPRY2 [plasma membrane] (Canis familiaris)
phospho-p-S112,S121-SPRY2 [plasma membrane] (Danio rerio)
phospho-p-S112,S121-SPRY2 [plasma membrane] (Drosophila melanogaster)
phospho-p-S112,S121-SPRY2 [plasma membrane] (Gallus gallus)
phospho-p-S112,S121-SPRY2 [plasma membrane] (Mus musculus)
phospho-p-S112,S121-SPRY2 [plasma membrane] (Rattus norvegicus)
phospho-p-S112,S121-SPRY2 [plasma membrane] (Xenopus tropicalis)
Modified Residues
Name
O-phospho-L-serine at 112
Coordinate
112
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 121
Coordinate
121
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
PDB
Interactors (66)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P22681 CBL  6 0.856 17
 UniProt:P57075 UBS3A      0.666 4
 UniProt:Q9BQ66 KR412      0.666 4
 UniProt:Q5T7P3 LCE1B  1 0.666 4
 UniProt:O43741 PRKAB2  3 0.666 4
 UniProt:P32242 OTX1      0.666 4
 UniProt:P62993 GRB2  1 0.591 3
 UniProt:P26371 KRTAP5-9  1 0.556 3
 UniProt:Q99750 MDFI      0.556 3
 UniProt:Q5TA82 LCE2D  1 0.556 3
 UniProt:Q9NVQ4 FAIM1      0.556 3
 UniProt:Q12527 ATG11      0.556 3
 UniProt:Q9BYR0 KRTAP4-7  1 0.556 3
 UniProt:Q6P2C6 Q6P2C6      0.556 3
 UniProt:Q9UJV3-2 MID2      0.556 3
 UniProt:P07510-2 CHRNG      0.556 3
 UniProt:Q9H2X0 CHRD      0.556 3
 UniProt:Q8NEC5 CATSPER1  1 0.556 3
 UniProt:Q5T5A8 LCE3C  1 0.556 3
 UniProt:Q86UY0 Q86UY0      0.556 3
 IntAct:EBI-16428938 CCSB ISOFORM ID      0.556 3
 UniProt:Q9NUL5 SHFL      0.556 3
 IntAct:EBI-10171679 386682      0.556 3
 UniProt:P14770 GP9  1 0.556 3
 UniProt:Q17RB8 LONRF1  1 0.556 3
 UniProt:Q02930-3 CREB5      0.556 3
 UniProt:P32502  1 0.556 3
 UniProt:Q5JPT6 Q5JPT6      0.556 3
 UniProt:Q06455-4 RUNX1T1      0.556 3
 UniProt:Q8TF42 UBS3B      0.556 3
 UniProt:Q5TA78 LCE4A  1 0.556 3
 UniProt:Q12259 YL108      0.556 3
 UniProt:Q9UKS6 PACSIN3  1 0.556 3
 UniProt:Q96MH2 HEXI2      0.556 3
 UniProt:O60336 MABP1      0.556 3
 UniProt:P06782  5 0.556 3
 UniProt:Q9Y4C2 TCAF1      0.556 3
 UniProt:Q14847 LASP1      0.556 3
 UniProt:Q9Y2K6 USP20  1 0.556 3
 UniProt:O75716 STK16      0.556 3
 UniProt:P29972 AQP1  1 0.556 3
 UniProt:Q9Y223 GNE  9 0.556 3
 IntAct:EBI-10173330 386677      0.556 3
 UniProt:O60573 EIF4E2  1 0.556 3
 UniProt:Q96SQ5 ZNF587  1 0.556 3
 UniProt:P60412 KRTAP10-11  1 0.556 3
 UniProt:Q8IUH5 ZDH17      0.556 3
 UniProt:P60410 KRTAP10-8  1 0.556 3
 UniProt:P60411 KRTAP10-9  1 0.556 3
 UniProt:P43115-12 PTGER3      0.556 3
 UniProt:Q6L8G9 KRTAP5-6  1 0.556 3
 UniProt:O43609 SPRY1  3 0.556 3
 UniProt:P60370 KRTAP10-5  1 0.556 3
 UniProt:Q9BYQ2 KRTAP9-4  1 0.556 3
 UniProt:P28799 GRN  2 0.556 3
 UniProt:Q5T5B0 LCE3E  1 0.556 3
 UniProt:Q9BYQ6 KRTAP4-11  1 0.556 3
 UniProt:P50222 MEOX2      0.556 3
 UniProt:Q9H2F3 HSD3B7  1 0.556 3
 UniProt:Q9BYQ4 KRTAP9-2  1 0.556 3
 UniProt:Q8TAU3 ZNF417  1 0.556 3
 UniProt:Q8WXE1 ATRIP  1 0.556 3
 UniProt:O43559 FRS3  3 0.556 3
 UniProt:O75791 GRAP2  1 0.556 3
 UniProt:O43639 NCK2  1 0.556 3
 UniProt:Q96B97 SH3KBP1  3 0.499 2