Positive gene expression regulation by 'CDK4 [nucleoplasm]'

Stable Identifier
R-HSA-936001
Type
PositiveGeneExpressionRegulation
Locations in the PathwayBrowser
General

As inferred from mouse, Cdk4 interacts with PPARG and enhances transcription. Binding of the two factors was tested on the FABP4 (aP2) promoter.

Literature References
PubMed ID Title Journal Year
16213226 Cdk4 promotes adipogenesis through PPARgamma activation

Abella, A, Dubus, P, Malumbres, M, Rane, SG, Kiyokawa, H, Sicard, A, Vignon, F, Langin, D, Barbacid, M, Fajas, L

Cell Metab 2005
Regulation participants
Regulation type
PositiveGeneExpressionRegulation
Regulated entity
Regulator