Reactome: A Curated Pathway Database

K48polyUb-TRAF3

Stable Identifier
R-HSA-936556
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
K48-polyubiquitin TRAF3
Locations in the PathwayBrowser
Literature References
External Reference Information
External Reference
Gene Names
TRAF3, CAP1, CRAF1
Chain
chain:1-568
Reference Genes
Reference Transcript
Other Identifiers
 0000940739  11742091_a_at  11743501_a_at  11759502_at  16789080
 1FLK  1FLL  1KZZ  1L0A  1RF3
 1ZMS  208315_3p_x_at  208315_x_at  221571_at  2933
 2ECY  2GKW  3553338  3553346  3553358
 3553359  3553363  3553364  3553367  3553368
 3553370  3553374  3553382  3553383  3553384
 37057_s_at  43952_at  7187  7977018  A_23_P37068
 A_32_P89837  AAA56753  AAA65732  AAA68195  AAC50112
 AAD29276  AAH75086  AAH75087  AF110908  AK303172
 AL117209  BAH13910  BC075086  BC075087  BX247977
 CAD62311  CCDS55946  CCDS9975  ENSG00000131323  ENSP00000376500
 ENSP00000445998  ENSP00000454207  ENST00000392745  ENST00000539721  ENST00000560371
 EntrezGene:7187  g4507678_3p_a_at  g4507678_3p_at  g4507678_3p_x_at  GE59008
 GO:0001817  GO:0002224  GO:0002376  GO:0003674  GO:0004842
 GO:0004871  GO:0005164  GO:0005515  GO:0005575  GO:0005622
 GO:0005623  GO:0005737  GO:0005739  GO:0005768  GO:0005829
 GO:0005886  GO:0006464  GO:0006915  GO:0006950  GO:0007165
 GO:0008063  GO:0008150  GO:0008219  GO:0008270  GO:0009058
 GO:0009898  GO:0016567  GO:0016579  GO:0016740  GO:0019899
 GO:0019901  GO:0019903  GO:0030162  GO:0031410  GO:0031625
 GO:0031996  GO:0032088  GO:0032480  GO:0032648  GO:0033209
 GO:0034641  GO:0035631  GO:0035666  GO:0042981  GO:0043167
 GO:0043226  GO:0044403  GO:0045087  GO:0046872  GO:0050688
 HGNC:12033  HPA002933  Hs.297660.1.S2_3p_at  Hs.510528  ILMN_1793154
 ILMN_2383774  IPR001293  IPR001841  IPR002083  IPR008974
 IPR012227  IPR013083  IPR017907  IPR027128  L38509
 LRG_229  LRG_229t1  NM_001199427  NM_003300  NP_001186356
 NP_003291  PF02176  PH_hs_0015383  PH_hs_0038599  SM00061
 TC14000786.hg  TRAF3  TRAF3-203  TRAF3-204  TRAF3-208
 U15637  U15637_s_at  U19260  U21092  uc001ymc.3
 uc001ymd.3  uc010txy.3  UPI000000CBF9  UPI0001E88EE1  XM_011537118
 XM_017021617  XM_017021618  XP_011535420  XP_016877106  XP_016877107
Participant Of
Other forms of this molecule
Modified Residues
Name Coordinate Modification PsiMod
ubiquitinylated lysine (K48polyUb [cytosol]) at unknown position K48polyUb [cytosol]
ubiquitinylated lysine [MOD:01148] A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
UCSC human
GeneCards
DOCK Blaster
PRO
Orphanet
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.702 Q92844 TANK_HUMAN 4
0.675 Q13546 RIPK1_HUMAN 4
0.639 Q8TDR0 MIPT3_HUMAN 8
0.635 Q99558 M3K14_HUMAN 3
0.635 O00463 TRAF5_HUMAN 3
0.633 O43353 RIPK2_HUMAN 5
0.508 P25942 TNR5_HUMAN 3
0.499 A2APF7 A2APF7_MOUSE 2
0.499 P15314 IRF1_MOUSE 2
0.499 Q9QYP6 AZI2_MOUSE 2
0.488 Q16543 CDC37_HUMAN 2
0.488 Q52MB2 CC184_HUMAN 2
0.488 Q96HA1-2 POM121 2
0.488 Q8IYE1 CCD13_HUMAN 2
0.488 Q86UB2 BIVM_HUMAN 2
0.488 Q8NAM6 ZSCA4_HUMAN 2
0.488 Q6ZSB9 ZBT49_HUMAN 2
0.488 P54725 RD23A_HUMAN 2
0.488 EBI-12191689 HEMGN 2
0.488 Q17RL8 Q17RL8_HUMAN 2
0.488 O95721 SNP29_HUMAN 2
0.488 P28062-2 PSMB8 2
0.488 Q5T681 CJ062_HUMAN 2
0.488 Q8TBB1 LNX1_HUMAN 2
0.488 Q0D2K3 RIPP1_HUMAN 2
0.488 Q9UKD1 GMEB2_HUMAN 2
0.488 O75928-2 PIAS2 2
0.488 Q8N9N2-2 ASCC1 2
0.488 Q96HA8 NTAQ1_HUMAN 2
0.488 Q96PC2 IP6K3_HUMAN 4
0.488 Q13114 TRAF3_HUMAN 2
0.488 Q9Y547 IFT25_HUMAN 2