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RYR1 [sarcoplasmic reticulum membrane]
Stable Identifier
R-HSA-937287
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
sarcoplasmic reticulum membrane
Synonyms
Ryanodine receptor 1, RYR1_HUMAN
Locations in the PathwayBrowser
Expand all
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Homo sapiens)
RYR tetramer:FKBP1B tetramer:CASQ polymer:TRDN:junctin [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR tetramers [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR1 tetramer [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR1 [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR tetramers [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR1 tetramer [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR1 [sarcoplasmic reticulum membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
RYR tetramers transport Ca2+ from sarcoplasmic reticulum lumen to cytosol (Homo sapiens)
RYR tetramer:FKBP1B tetramer:CASQ polymer:TRDN:junctin [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR tetramers [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR1 tetramer [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR1 [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR tetramers [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR1 tetramer [sarcoplasmic reticulum membrane] (Homo sapiens)
RYR1 [sarcoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P21817 RYR1
Gene Names
RYR1, RYDR
Chain
chain:1-5038
Reference Genes
BioGPS Gene:6261 RYR1
COSMIC (genes):RYR1 RYR1
CTD Gene:6261 RYR1
dbSNP Gene:6261 RYR1
ENSEMBL:ENSG00000196218 RYR1
HGNC:10483 RYR1
KEGG:hsa:6261 RYR1
Monarch:6261 RYR1
NCBI Gene:6261 RYR1
OMIM:180901 RYR1
UCSC:P21817 RYR1
Reference Transcript
RefSeq:NM_000540.2 RYR1
RefSeq:NM_001042723.1 RYR1
Other Identifiers
11730388_a_at
11730389_at
16861734
205485_PM_at
205485_at
3737910
37990_at
3832458
3832459
3832460
3832461
3832462
3832463
3832465
3832466
3832468
3832469
3832470
3832471
3832472
3832473
3832476
3832477
3832478
3832479
3832480
3832481
3832483
3832484
3832486
3832487
3832488
3832489
3832490
3832491
3832492
3832493
3832494
3832495
3832496
3832497
3832498
3832499
3832501
3832502
3832503
3832504
3832505
3832506
3832507
3832508
3832509
3832510
3832511
3832512
3832513
3832514
3832515
3832516
3832517
3832518
3832519
3832520
3832522
3832523
3832524
3832525
3832526
3832529
3832530
3832531
3832532
3832533
3832534
3832535
3832536
3832538
3832539
3832540
3832541
3832542
3832543
3832544
3832545
3832546
3832547
3832548
3832550
3832551
3832552
3832553
3832554
3832555
3832556
3832557
3832559
3832560
3832561
3832562
3832563
3832564
3832565
3832566
3832568
3832569
3832570
3832571
3832577
3832578
3832579
3832583
3832584
3832585
3832586
3832587
3832588
3832589
3832590
3832591
3832592
3832593
3832594
3832595
3832596
3832597
3832598
3832599
3832600
3832601
3832603
3832605
3832607
3832611
3832612
6261
8028407
A_14_P120714
A_14_P130348
A_14_P138065
A_23_P78867
A_24_P170544
GE60539
GO:0001666
GO:0003012
GO:0003151
GO:0005215
GO:0005216
GO:0005219
GO:0005245
GO:0005262
GO:0005509
GO:0005515
GO:0005516
GO:0005524
GO:0005737
GO:0005783
GO:0005790
GO:0005886
GO:0005938
GO:0006811
GO:0006816
GO:0006874
GO:0006936
GO:0006941
GO:0008324
GO:0014701
GO:0014802
GO:0014808
GO:0015278
GO:0016020
GO:0016529
GO:0019722
GO:0030018
GO:0031000
GO:0031090
GO:0031674
GO:0033017
GO:0034704
GO:0042383
GO:0043226
GO:0043588
GO:0043931
GO:0046872
GO:0048741
GO:0048763
GO:0048856
GO:0051209
GO:0051289
GO:0051480
GO:0055085
GO:0065003
GO:0070062
GO:0070588
GO:0071277
GO:0071313
GO:1990425
HMNXSV003039429
ILMN_1682062
ILMN_2411781
J05200_rna1_s_at
PH_hs_0041148
TC19000530.hg
TC19002127.hg
g10863870_3p_at
Participates
as a component of
RYR1 tetramer [sarcoplasmic reticulum membrane] (Homo sapiens)
Inferred To
RYR1 [sarcoplasmic reticulum membrane]
(Bos taurus)
RYR1 [sarcoplasmic reticulum membrane]
(Canis familiaris)
RYR1 [sarcoplasmic reticulum membrane]
(Mus musculus)
RYR1 [sarcoplasmic reticulum membrane]
(Rattus norvegicus)
Cross References
Guide to Pharmacology - Targets
747
ENSEMBL
ENST00000355481
,
ENSP00000347667
,
ENST00000359596
,
ENSP00000352608
OpenTargets
ENSG00000196218
ZINC - Substances
RYR1_HUMAN
ZINC target
P21817
PRO
P21817
GlyGen
P21817
PDB
6UHS
,
6UHI
HPA
ENSG00000196218-RYR1
Pharos - Targets
P21817
Orphanet
RYR1
ZINC - Predictions - Purchasable
RYR1_HUMAN
HMDB Protein
HMDBP07974
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