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RGS14 [plasma membrane]
Stable Identifier
R-HSA-939780
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Regulator of G-protein signaling 14, RGS14_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Active G alpha (i)–i1/i2/i3 binds RGS proteins (Homo sapiens)
G alpha (i):GTP:RGS [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS14 [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS14 [plasma membrane] (Homo sapiens)
G alpha (i) auto-inactivates by hydrolysing GTP to GDP (Homo sapiens)
RGS proteins active for G alpha (i) [plasma membrane] (Homo sapiens)
RGS14 [plasma membrane] (Homo sapiens)
G alpha (i):RGS dissociates to inactive G alpha (i)–i1/i2/i3 (Homo sapiens)
G alpha (i):GDP:RGS [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS14 [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS14 [plasma membrane] (Homo sapiens)
G alpha (i)–i1/i2/i3 in G (i):RGS complex is inactivated (Homo sapiens)
G alpha (i):GDP:RGS [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS14 [plasma membrane] (Homo sapiens)
G alpha (i):GTP:RGS [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS14 [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
RGS14 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43566 RGS14
Gene Names
RGS14
Chain
chain:1-566
Reference Genes
BioGPS Gene:10636 RGS14
COSMIC (genes):RGS14 RGS14
CTD Gene:10636 RGS14
dbSNP Gene:10636 RGS14
ENSEMBL:ENSG00000169220 RGS14
ENSEMBL_homo_sapiens_GENE:ENSG00000169220.18 RGS14
HGNC:9996 RGS14
KEGG Gene (Homo sapiens):10636 RGS14
Monarch:10636 RGS14
NCBI Gene:10636 RGS14
OMIM:602513 RGS14
UCSC:O43566 RGS14
Reference Transcript
RefSeq:NM_006480.4 RGS14
Other Identifiers
10636
11748699_a_at
11754685_a_at
16993041
204280_3p_at
204280_PM_at
204280_at
211021_PM_s_at
211021_s_at
2843094
2843095
2843096
2843101
2843102
2843103
2843104
2843106
2843108
2843111
2843112
2843113
2843116
2843118
2843120
2843121
2843123
2843126
2843127
2843128
2843129
38290_PM_at
38290_at
4877400C_3p_at
52325_at
8110327
A_23_P124927
GE54295
GO:0000278
GO:0000922
GO:0001965
GO:0003824
GO:0003924
GO:0005092
GO:0005096
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005813
GO:0005815
GO:0005819
GO:0005856
GO:0005874
GO:0005886
GO:0006351
GO:0006355
GO:0006913
GO:0006979
GO:0007010
GO:0007049
GO:0007051
GO:0007059
GO:0007165
GO:0007186
GO:0007612
GO:0007616
GO:0008017
GO:0008092
GO:0008277
GO:0008542
GO:0009968
GO:0010070
GO:0014069
GO:0016020
GO:0016604
GO:0016605
GO:0016787
GO:0019901
GO:0023052
GO:0030154
GO:0030159
GO:0030425
GO:0030695
GO:0031914
GO:0032794
GO:0036211
GO:0042995
GO:0043197
GO:0043226
GO:0043407
GO:0043620
GO:0045202
GO:0045744
GO:0048008
GO:0048856
GO:0050769
GO:0050804
GO:0050877
GO:0051301
GO:0060090
GO:0060291
GO:0070373
GO:0098772
GO:0098978
HMNXSV003057611
ILMN_1696828
PH_hs_0000974
TC05001013.hg
g5454005_3p_at
g5454005_3p_s_at
Participates
as a member of
RGS proteins active for G alpha (i) [plasma membrane] (Homo sapiens)
RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)
Inferred To
Rgs14 [plasma membrane]
(Mus musculus)
Rgs14 [plasma membrane]
(Rattus norvegicus)
loco [plasma membrane]
(Drosophila melanogaster)
rgs14 [plasma membrane]
(Xenopus tropicalis)
RGS14 [plasma membrane]
(Bos taurus)
RGS14 [plasma membrane]
(Canis familiaris)
RGS14 [plasma membrane]
(Gallus gallus)
RGS14 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_006471.2
Guide to Pharmacology - Targets
2820
OpenTargets
ENSG00000169220
GeneCards
O43566
HPA
ENSG00000169220-RGS14
Ensembl
ENSG00000169220
,
ENST00000408923
,
ENSP00000386229
PRO
O43566
Pharos - Targets
O43566
PDB
2XNS
,
3ONW
,
2OM2
,
2JNU
,
3QI2
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