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UBE2Q2 [cytosol]
Stable Identifier
R-HSA-947618
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ubiquitin-conjugating enzyme E2 Q2, UB2Q2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2Q2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2Q2 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2Q2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2Q2 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2Q2 [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2Q2 [cytosol] (Homo sapiens)
Transfer of ubiquitin from E1 to E2 (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2Q2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2Q2 [cytosol] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Protein ubiquitination (Homo sapiens)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)
UBA1 conjugates ubiquitin to cytosolic E2 enzymes (Homo sapiens)
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Homo sapiens)
UBE2Q2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8WVN8 UBE2Q2
Gene Names
UBE2Q2
Chain
chain:1-375
Reference Genes
BioGPS Gene:92912 UBE2Q2
COSMIC (genes):UBE2Q2 UBE2Q2
CTD Gene:92912 UBE2Q2
dbSNP Gene:92912 UBE2Q2
ENSEMBL:ENSG00000140367 UBE2Q2
ENSEMBL_homo_sapiens_GENE:ENSG00000140367.12 UBE2Q2
HGNC:19248 UBE2Q2
KEGG Gene (Homo sapiens):92912 UBE2Q2
Monarch:92912 UBE2Q2
NCBI Gene:92912 UBE2Q2
OMIM:612501 UBE2Q2
UCSC:Q8WVN8 UBE2Q2
Reference Transcript
RefSeq:NM_001145335.1 UBE2Q2
RefSeq:NM_001284382.1 UBE2Q2
RefSeq:NM_173469.3 UBE2Q2
Other Identifiers
11716198_a_at
11716199_x_at
11716200_s_at
11741570_a_at
11755298_s_at
16803251
224747_PM_at
224747_at
3143481
3586335
3602498
3602499
3602500
3602501
3602502
3602503
3602504
3602505
3602506
3602508
3602509
3602510
3602512
3602514
3602515
3602518
3602519
3602521
3602523
3602524
3602525
3604645
3604726
3616479
4031991
4031993
4037268
7985044
92912
A_14_P111780
A_24_P412617
A_33_P3333826
GE904213
GO:0000166
GO:0003824
GO:0004842
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0016567
GO:0016740
GO:0036211
GO:0043226
GO:0061631
GO:0070936
GO:0140096
HMNXSV003045120
Hs.95262.0.S1_3p_at
ILMN_1683817
PH_hs_0005204
TC15000704.hg
Participates
as a member of
E2 ubiquitin conjugating enzyme (UBA1 substrate) [cytosol] (Homo sapiens)
as a candidate of
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
Other forms of this molecule
Ub-C304-UBE2Q2 [cytosol]
Inferred To
Ube2q2 [cytosol]
(Mus musculus)
Ube2q2 [cytosol]
(Rattus norvegicus)
Dmel\CG2924 [cytosol]
(Drosophila melanogaster)
ubc-25 [cytosol]
(Caenorhabditis elegans)
UBE2Q2 [cytosol]
(Bos taurus)
UBE2Q2 [cytosol]
(Gallus gallus)
Cross References
RefSeq
NP_001271311.1
,
NP_775740.1
,
NP_001138807.1
OpenTargets
ENSG00000140367
HPA
ENSG00000140367-UBE2Q2
GeneCards
Q8WVN8
Ensembl
ENSP00000267938
,
ENST00000267938
,
ENST00000569423
,
ENSP00000456324
,
ENSG00000140367
,
ENST00000561851
,
ENSP00000456229
PRO
Q8WVN8
Pharos - Targets
Q8WVN8
HMDB Protein
HMDBP09326
PDB
1ZUO
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04792 HSBP1
3
HSPB1 [cytosol]
(R-HSA-450563)
p-S15,S78,S82-HSP27 [cytosol]
(R-HSA-5218697)
p-S78,S82 HSPB1 [cytosol]
(R-HSA-5687009)
0.556
3
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