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UBE2V2 [cytosol]
Stable Identifier
R-HSA-947624
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ubiquitin-conjugating enzyme E2 variant 2, UB2V2_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2V2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2V2 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2V2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2V2 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2V2 [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2V2 [cytosol] (Homo sapiens)
Transfer of ubiquitin from E1 to E2 (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2V2 [cytosol] (Homo sapiens)
Ubiquitin:E2 conjugating enzymes [cytosol] (Homo sapiens)
E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)
UBE2V2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15819 UBE2V2
Gene Names
UBE2V2, MMS2, UEV2
Chain
initiator methionine:1, chain:2-145
Reference Genes
BioGPS Gene:7336 UBE2V2
COSMIC (genes):UBE2V2 UBE2V2
CTD Gene:7336 UBE2V2
dbSNP Gene:7336 UBE2V2
ENSEMBL:ENSG00000169139 UBE2V2
HGNC:12495 UBE2V2
KEGG Gene (Homo sapiens):7336 UBE2V2
Monarch:7336 UBE2V2
NCBI Gene:7336 UBE2V2
OMIM:603001 UBE2V2
UCSC:Q15819 UBE2V2
Reference Transcript
RefSeq:NM_003350.2 UBE2V2
Other Identifiers
0006400070
11727093_s_at
11754112_a_at
209096_at
228734_at
230411_at
3097218
3097222
3097223
3097226
3097227
3097228
3097229
3097230
3097232
37750_at
52701_at
53558_at
7336
8146379
83354_r_at
A_24_P406514
A_33_P3333810
GE54423
GO:0000209
GO:0000729
GO:0003674
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0006259
GO:0006282
GO:0006301
GO:0006303
GO:0006464
GO:0006950
GO:0008150
GO:0008219
GO:0009056
GO:0010976
GO:0016567
GO:0022607
GO:0030154
GO:0031372
GO:0032436
GO:0032991
GO:0034330
GO:0034641
GO:0042275
GO:0043226
GO:0043524
GO:0045739
GO:0048856
GO:0051965
GO:0061631
GO:0070062
GO:0070534
Hs.247848.0.S1_3p_s_at
Hs.30662.0.A1_3p_at
Hs.43569.0.A1_3p_at
ILMN_1770515
ILMN_2076567
PH_hs_0029906
TC08000348.hg
U62136_at
g4775663_3p_at
Participant Of
hasCandidate
E2 Ubiquitin-conjugating enzyme [cytosol]
Other forms of this molecule
UBE2V2 [nucleoplasm]
Inferred To
Ube2v2 [cytosol] (Mus musculus)
Ube2v2 [cytosol] (Rattus norvegicus)
Uev1A [cytosol] (Drosophila melanogaster)
spm2 [cytosol] (Schizosaccharomyces pombe)
ube2v2 [cytosol] (Danio rerio)
ube2v2 [cytosol] (Xenopus tropicalis)
MMS2 [cytosol] (Saccharomyces cerevisiae)
uev-1 [cytosol] (Caenorhabditis elegans)
UBE2V2 [cytosol] (Bos taurus)
UBE2V2 [cytosol] (Canis familiaris)
UBE2V2 [cytosol] (Gallus gallus)
UBE2V2 [cytosol] (Plasmodium falciparum)
UBE2V2 [cytosol] (Sus scrofa)
ube2v [cytosol] (Dictyostelium discoideum)
Cross References
RefSeq
NP_003341.1
OpenTargets
ENSG00000169139
HPA
ENSG00000169139-UBE2V2
GeneCards
Q15819
Ensembl
ENST00000523111
,
ENSG00000169139
,
ENSP00000428209
PRO
Q15819
PDB
4NRI
,
1J74
,
5AIT
,
3VON
,
4NRG
,
4ORH
,
4NR3
,
4ONM
,
1J7D
,
4ONL
,
4ONN
,
1ZGU
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P61088 UBE2N
5
Ub-C87-UBE2N [cytosol]
(R-HSA-8864210)
Ub-C87-UBE2N [nucleoplasm]
(R-HSA-8943013)
K63polyUb-C87-UBE2N [nucleoplasm]
(R-HSA-6790511)
UBE2N [nucleoplasm]
(R-HSA-5682541)
UBE2N [cytosol]
(R-HSA-206072)
0.751
5
UniProt:P00533 EGFR
59
p-5Y-EGFRvIII [plasma membrane]
(R-HSA-1248649)
p-6Y-EGFR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869138)
EGFRvIII [plasma membrane]
(R-HSA-1214162)
p-6Y-EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1182985)
p-6Y-EGFR L858R;T790M [plasma membrane]
(R-HSA-1182984)
p-6Y-EGFR M766_A767insASV [plasma membrane]
(R-HSA-1996343)
p-6Y-EGFR D770_N771insNPH [plasma membrane]
(R-HSA-1996342)
p-6Y-EGFR V738_K739insKIPVAI [plasma membrane]
(R-HSA-1996346)
p-6Y-EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996335)
p-6Y-EGFR E746_A750del [plasma membrane]
(R-HSA-1181214)
p-6Y-EGFR L858R [plasma membrane]
(R-HSA-1173211)
p-6Y-EGFR G719S [plasma membrane]
(R-HSA-1169417)
p-6Y-EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228038)
p-6Y-EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228044)
p-6Y-EGFR L747_T751del [plasma membrane]
(R-HSA-1228041)
p-6Y-EGFR L747_S752del [plasma membrane]
(R-HSA-1228040)
p-6Y-EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228042)
p-6Y-EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228037)
p-6Y-EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228039)
p-6Y-EGFR L861Q [plasma membrane]
(R-HSA-1177541)
p-6Y-EGFR A289V [plasma membrane]
(R-HSA-1996334)
p-6Y-EGFR T263P [plasma membrane]
(R-HSA-1996336)
p-6Y-EGFR G598V [plasma membrane]
(R-HSA-1996339)
p-6Y-EGFR R108K [plasma membrane]
(R-HSA-1996338)
p-6Y-EGFR A289T [plasma membrane]
(R-HSA-1996341)
p-6Y-EGFR G719C [plasma membrane]
(R-HSA-1177530)
p-6Y-EGFR A289D [plasma membrane]
(R-HSA-1996340)
p-6Y-EGFR G719A [plasma membrane]
(R-HSA-1177528)
EGFR L858R;T790M [plasma membrane]
(R-HSA-1181386)
EGFR E746_A750del;T790M [plasma membrane]
(R-HSA-1181399)
EGFR D770_N771insNPG [plasma membrane]
(R-HSA-1996322)
EGFR V738_K739insKIPVAI [plasma membrane]
(R-HSA-1996325)
EGFR M766_A767insASV [plasma membrane]
(R-HSA-1996326)
EGFR D770_N771insNPH [plasma membrane]
(R-HSA-1996317)
EGFR L858R [plasma membrane]
(R-HSA-1173212)
EGFR G719S [plasma membrane]
(R-HSA-1169418)
EGFR E746_A750del [plasma membrane]
(R-HSA-1181211)
EGFR L747_P753delinsS [plasma membrane]
(R-HSA-1228010)
EGFR A289V [plasma membrane]
(R-HSA-1996321)
EGFR L747_T751delinsP [plasma membrane]
(R-HSA-1228012)
EGFR L747_T751del [plasma membrane]
(R-HSA-1228015)
EGFR A289D [plasma membrane]
(R-HSA-1996327)
EGFR L861Q [plasma membrane]
(R-HSA-1177542)
EGFR R108K [plasma membrane]
(R-HSA-1996330)
EGFR L747_A750delinsP [plasma membrane]
(R-HSA-1228034)
EGFR E746_T751delinsA [plasma membrane]
(R-HSA-1228031)
EGFR G719A [plasma membrane]
(R-HSA-1177532)
EGFR A289T [plasma membrane]
(R-HSA-1996306)
EGFR E746_S752delinsV [plasma membrane]
(R-HSA-1228025)
EGFR G719C [plasma membrane]
(R-HSA-1177531)
EGFR T263P [plasma membrane]
(R-HSA-1996315)
EGFR G598V [plasma membrane]
(R-HSA-1996314)
EGFR L747_S752del [plasma membrane]
(R-HSA-1228016)
EGFR [endosome membrane]
(R-HSA-9611160)
p-4Y-EGFR [plasma membrane]
(R-HSA-180287)
p-Y992,Y1045,Y1068,Y1086,Y1173-EGFR [plasma membrane]
(R-HSA-8864019)
p-Y1086,Y1101-EGFR [plasma membrane]
(R-HSA-179868)
EGFR [plasma membrane]
(R-HSA-179837)
p-6Y-EGFR [plasma membrane]
(R-HSA-179803)
0.553
2
UniProt:Q14527 HLTF
1
HLTF [nucleoplasm]
(R-HSA-8855007)
0.462
2
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