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BRS3 [plasma membrane]
Stable Identifier
R-HSA-947694
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Bombesin receptor subtype-3, BRS3_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
BRS3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
BRS3 [plasma membrane] (Homo sapiens)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
BRS3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
BRS3 [plasma membrane] (Homo sapiens)
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
GPCRs that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
BRS3 [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
BRS3 [plasma membrane] (Homo sapiens)
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Peptide ligand-binding receptors (Homo sapiens)
Bombesin-like receptors bind bombesin homologues (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
BRS3 [plasma membrane] (Homo sapiens)
Bombesin-like receptor:bombesin-like peptide [plasma membrane] (Homo sapiens)
Bombesin-like receptor [plasma membrane] (Homo sapiens)
BRS3 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P32247 BRS3
Gene Names
BRS3
Chain
chain:1-399
Reference Genes
BioGPS Gene:680 BRS3
COSMIC (genes):BRS3 BRS3
CTD Gene:680 BRS3
dbSNP Gene:680 BRS3
ENSEMBL:ENSG00000102239 BRS3
ENSEMBL_homo_sapiens_GENE:ENSG00000102239.5 BRS3
HGNC:1113 BRS3
KEGG Gene (Homo sapiens):680 BRS3
Monarch:680 BRS3
NCBI Gene:680 BRS3
OMIM:300107 BRS3
UCSC:P32247 BRS3
Reference Transcript
RefSeq:NM_001727.1 BRS3
Other Identifiers
11737304_at
1552818_PM_a_at
1552818_a_at
17107287
207369_PM_at
207369_at
35128_at
3992511
3992513
3992514
3992515
3992516
3992518
3992519
3992520
680
8170159
A_23_P33961
GE687749
GE80634
GO:0003013
GO:0004930
GO:0004946
GO:0005886
GO:0005975
GO:0006006
GO:0007165
GO:0007186
GO:0007218
GO:0008188
GO:0008217
GO:0008343
GO:0008528
GO:0016020
GO:0023052
GO:0031989
GO:0060089
HMNXSV003011899
Hs.121484.0.S2_3p_at
Hs2.121484.1.S1_3p_s_at
ILMN_1756165
PH_hs_0006756
TC0X000660.hg
X76498_at
Participates
as a candidate of
Bombesin-like receptor [plasma membrane] (Homo sapiens)
Inferred To
CCHa1-R [plasma membrane]
(Drosophila melanogaster)
Homologues of BRS3 [plasma membrane]
(Drosophila melanogaster)
CCHa2-R [plasma membrane]
(Drosophila melanogaster)
brs3 [plasma membrane]
(Xenopus tropicalis)
BRS3 [plasma membrane]
(Bos taurus)
BRS3 [plasma membrane]
(Canis familiaris)
BRS3 [plasma membrane]
(Sus scrofa)
BRS3.5 [plasma membrane]
(Gallus gallus)
Brs3 [plasma membrane]
(Mus musculus)
Brs3 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_001718.1
Guide to Pharmacology - Targets
40
OpenTargets
ENSG00000102239
ZINC - Substances
BRS3_HUMAN
ZINC target
P32247
PRO
P32247
ZINC - Investigational
BRS3_HUMAN
HPA
ENSG00000102239-BRS3
GeneCards
P32247
Ensembl
ENSP00000359682
,
ENST00000370648
,
ENSG00000102239
Pharos - Targets
P32247
ZINC - Predictions - Purchasable
BRS3_HUMAN
HMDB Protein
HMDBP07474
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