SAE1

Stable Identifier
R-HSA-947697
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SUMO-activating enzyme subunit 1, SAE1_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
11481243 Expression and regulation of the mammalian SUMO-1 E1 enzyme

Azuma, Y, Tan, SH, Cavenagh, MM, Ainsztein, AM, Saitoh, H, Dasso, M

FASEB J. 2001
External Reference Information
External Reference
UniProt:Q9UBE0 SAE1
Gene Names
SAE1, AOS1, SUA1, UBLE1A
Chain
initiator methionine:1, chain:1-346, chain:2-346
Reference Genes
BioGPS Gene:10055 SAE1
COSMIC (genes):SAE1 SAE1
CTD Gene:10055 SAE1
dbSNP Gene:10055 SAE1
ENSEMBL:ENSG00000142230 SAE1
ENSEMBL:ENSG00000142230 SAE1
HGNC:30660 SAE1
KEGG Gene (Homo sapiens):hsa:10055 SAE1
Monarch:10055 SAE1
NCBI Gene:10055 SAE1
OMIM:613294 SAE1
UCSC:Q9UBE0 SAE1
Reference Transcript
Other Identifiers
0000060338
10055
11737533_a_at
11744108_x_at
11751729_a_at
11751730_x_at
1555618_s_at
1Y8Q
1Y8R
217946_s_at
3353524
3353529
3837140
3837141
3837142
3837143
3837146
3837147
3837148
3837150
3837151
3837152
3837162
3837164
3837167
3837168
3837169
3837170
3837171
3837172
3837173
3837174
3837175
3837176
3KYC
3KYD
41906
43552
45712_at
51084_at
8029884
A0A024R0R4
A_14_P101357
A_23_P16337
A_24_P194000
AAD12785
AAD23902
AAD24433
AAF29104
AAH00344
AAH03611
AAH18271
AAP35954
AC008532
AC008755
AF046025
AF090385
AF110956
AF161489
AK021978
AK315624
AL560234
B3KNJ4
BAG37992
BAG51064
BC000344
BC003611
BC018271
BT007290
CCDS12696
CCDS54284
CCDS54285
CH471126
EAW57461
EAW57462
EAW57463
ENSG00000142230
ENSP00000270225
ENSP00000416557
ENSP00000440818
ENST00000270225
ENST00000392776
ENST00000413379
EntrezGene:10055
g7705472_3p_s_at
GE61854
GO:0003674
GO:0004839
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005654
GO:0005737
GO:0006464
GO:0006605
GO:0006810
GO:0007005
GO:0008022
GO:0008047
GO:0008150
GO:0008641
GO:0016567
GO:0016874
GO:0016925
GO:0019899
GO:0019948
GO:0030234
GO:0031510
GO:0032991
GO:0043008
GO:0043085
GO:0043226
GO:0044388
GO:0046982
GO:1903955
HGNC:30660
HPA041906
HPA043552
Hs2.279868.2.S1_3p_s_at
ILMN_1657204
IPR000011
IPR000594
IPR035985
M0QX65
M0QYM8
M0QYP2
M0QZS6
M0R054
M0R286
M0R375
MIM:613294
NM_001145713
NM_001145714
NM_005500
NP_001139185
NP_001139186
NP_005491
PF00899
PH_hs_0022094
PR01849
SAE1
SAE1-201
SAE1-202
SAE1-203
TC19000672.hg
TC19002180.hg
uc002pgc.4
uc002pgd.4
uc010ekx.4
UPI0000037725
UPI000059D753
UPI0000D4CF03
XM_006722963
XM_006722965
XM_017026135
XM_017026136
XP_006723026
XP_006723028
XP_016881624
XP_016881625
Participant Of
hasComponent
Inferred To
Homologues of SAE1 [nucleoplasm] (Arabidopsis thaliana)
Homologues of SAE1 [nucleoplasm] (Drosophila melanogaster)
Homologues of SAE1 [nucleoplasm] (Sus scrofa)
SAE1 [nucleoplasm] (Arabidopsis thaliana)
SAE1 [nucleoplasm] (Bos taurus)
SAE1 [nucleoplasm] (Caenorhabditis elegans)
SAE1 [nucleoplasm] (Canis familiaris)
SAE1 [nucleoplasm] (Danio rerio)
SAE1 [nucleoplasm] (Dictyostelium discoideum)
SAE1 [nucleoplasm] (Drosophila melanogaster)
SAE1 [nucleoplasm] (Gallus gallus)
SAE1 [nucleoplasm] (Mus musculus)
SAE1 [nucleoplasm] (Oryza sativa)
SAE1 [nucleoplasm] (Plasmodium falciparum)
SAE1 [nucleoplasm] (Rattus norvegicus)
SAE1 [nucleoplasm] (Saccharomyces cerevisiae)
SAE1 [nucleoplasm] (Schizosaccharomyces pombe)
SAE1 [nucleoplasm] (Sus scrofa)
SAE1 [nucleoplasm] (Taeniopygia guttata)
SAE1 [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
ZINC - Metabolites
GeneCards
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
BRENDA (Homo sapiens)
ZINC - Predictions - Purchasable
HMDB Protein
PDB
Interactors (4)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P63165 SUMO1  155 0.656 3
 UniProt:P63279 UBE2I  8 0.564 2
 UniProt:Q02548 PAX5  1 0.488 2
 UniProt:P26367 PAX6  1 0.488 2