PEX19:PEX3 binds PEX16

Stable Identifier
R-HSA-9603797
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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The cytosolic PEX19:PEX3 complex binds PEX16 located in the peroxisomal membrane (inferred from human PEX19, human PEX16, and rat Pex3). Thus PEX16 serves as a docking factor. PEX3 is believed to be inserted in the peroxisomal membrane by this pathway and by direct co-translational insertion in the membrane of the endoplasmic reticulum that then buds to generate peroxisomes.
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