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CAMK2D [cytosol]
Stable Identifier
R-HSA-9611357
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Ca/Calmodulin dependent protein kinase II delta subunit
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Assembly and cell surface presentation of NMDA receptors (Homo sapiens)
CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Negative regulation of NMDA receptor-mediated neuronal transmission (Homo sapiens)
CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:LRRC7:CaMKII dodecamer [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
PPM1F dephosphorylates p-T286-CaMKII (Homo sapiens)
CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Post NMDA receptor activation events (Homo sapiens)
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Homo sapiens)
Ras activation upon Ca2+ influx through NMDA receptor (Homo sapiens)
Activation of RasGRF (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
NMDA-activated RASGRF1 activates RAS (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Long-term potentiation (Homo sapiens)
CaMKII autophosphorylates (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII binds activated NMDA receptor (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII binds activated calmodulin (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII phosphorylates AMPA receptor (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:p-Y-GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:p-Y-GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Unblocking of NMDA receptors, glutamate binding and activation (Homo sapiens)
Ca2+ influx into the post-synaptic cell (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors:p-T286-CaMKII dodecamer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Mg2+ binds GRIN1:GRIN2 NMDA receptors (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Unblocking of GRIN1:GRIN2 NMDA receptors (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
DAG and IP3 signaling (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
CaMK IV-mediated phosphorylation of CREB (Homo sapiens)
CaMKII autophosphorylates (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII binds activated calmodulin (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF/MAP kinase cascade (Homo sapiens)
RAS GEFs promote RAS nucleotide exchange (Homo sapiens)
RAS GEFs [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptor:RASGRF1 oligomer:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2B NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2B NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
PLC beta mediated events (Homo sapiens)
Ca-dependent events (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
CaMK IV-mediated phosphorylation of CREB (Homo sapiens)
CaMKII autophosphorylates (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII binds activated calmodulin (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
CaMKII dodecamer:CALM1:4xCa2+ [cytosol] (Homo sapiens)
CaMKII dodecamer [cytosol] (Homo sapiens)
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
CAMK2D [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q13557 CAMK2D
Gene Names
CAMK2D, CAMKD
Chain
initiator methionine:, chain:2-499
Reference Genes
COSMIC (genes):CAMK2D CAMK2D
dbSNP Gene:817 CAMK2D
ENSEMBL:ENSG00000145349 CAMK2D
Participates
as a candidate of
CAMK2A,CAMK2B,(CAMK2D,CAMK2G) [cytosol] (Homo sapiens)
Other forms of this molecule
p-T287-CAMK2D [plasma membrane]
p-T287-CAMK2D [nucleoplasm]
p-T287-CAMK2D [endocytic vesicle membrane]
p-T287-CAMK2D [cytosol]
Inferred To
CAMK2D [cytosol]
(Bos taurus)
CAMK2D [cytosol]
(Caenorhabditis elegans)
CAMK2D [cytosol]
(Danio rerio)
CAMK2D [cytosol]
(Drosophila melanogaster)
CAMK2D [cytosol]
(Gallus gallus)
CAMK2D [cytosol]
(Mus musculus)
CAMK2D [cytosol]
(Rattus norvegicus)
CAMK2D [cytosol]
(Sus scrofa)
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O96015 DNAL4
1
DNAL4 [plasma membrane]
(R-HSA-177484)
0.743
5
UniProt:Q8N0Z6 TTC5
3
TTC5 [nucleoplasm]
(R-HSA-6804264)
p-S203-TTC5 [nucleoplasm]
(R-HSA-6804261)
p-S203,S221-TTC5 [nucleoplasm]
(R-HSA-6804259)
0.666
4
UniProt:Q8N9N5 BANP
1
BANP [nucleoplasm]
(R-HSA-3221973)
0.666
4
UniProt:Q96PM5 RCHY1
2
RCHY1 [cytosol]
(R-HSA-976013)
RCHY1 [nucleoplasm]
(R-HSA-5655134)
0.499
2
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