ERBB4 gene expression is stimulated by ERBB4s80:ESR1

Stable Identifier
R-HSA-9612671
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm, plasma membrane
ReviewStatus
5/5
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ERBB4 gene expression is stimulated by ERBB4s80:ESR1
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The complex of intracellular fragment of ERBB4, ERBB4s80 (E4ICD) and activated estrogen receptor (ESR1:estrogen) stimulates transcription of the ERBB4 gene (Zhu et al. 2006).
Literature References
PubMed ID Title Journal Year
16912174 Coregulation of estrogen receptor by ERBB4/HER4 establishes a growth-promoting autocrine signal in breast tumor cells

Nair, SS, Vadlamudi, RK, Marrero, L, Zhu, Y, Jones, FE, Williams, CC, Pandey, AK, Sullivan, LL

Cancer Res 2006
Participants
Input
Output
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as an event of
This event is regulated
Positively by
Regulator
ERBB4s80:ESR1:estrogen:ERBB4 gene [nucleoplasm] (Homo sapiens)
Authored
Stern, DF  (2019-02-21)
Orlic-Milacic, M  (2018-06-28)
Created
Orlic-Milacic, M  (2018-06-29)
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