Reactome | ID3 [nucleoplasm]

ID3 [nucleoplasm]

Stable Identifier

R-HSA-9613379

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA-binding protein inhibitor ID-3, ID3_HUMAN

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by NTRKs (Homo sapiens)
    - Signaling by NTRK1 (TRKA) (Homo sapiens)
      - Nuclear Events (kinase and transcription factor activation) (Homo sapiens)
        
        NGF-stimulated transcription (Homo sapiens)
        
        ID1 and ID3 gene expression (Homo sapiens)
        
        ID1, ID3 [nucleoplasm] (Homo sapiens)
        
        ID3 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q02535 ID3

Gene Names

ID3, 1R21, BHLHB25, HEIR1

Chain

chain:1-119

Reference Genes

BioGPS Gene:3399 ID3

COSMIC (genes):ID3 ID3

CTD Gene:3399 ID3

dbSNP Gene:3399 ID3

ENSEMBL:ENSG00000117318 ID3

ENSEMBL_homo_sapiens_GENE:ENSG00000117318.9 ID3

ENSEMBL_homo_sapiens_GENE:ENSG00000283060.2 ID3

HGNC:5362 ID3

KEGG Gene (Homo sapiens):3399 ID3

Monarch:3399 ID3

NCBI Gene:3399 ID3

OMIM:600277 ID3

UCSC:Q02535 ID3

Reference Transcript

RefSeq:NM_002167.4 ID3

Other Identifiers

11716666_a_at

11754008_x_at

11757404_x_at

16683377

207826_PM_s_at

207826_s_at

2401492

2401494

2401495

2401497

2401498

2401500

2401501

3399

37043_at

67083_at

7913655

A_23_P137381

GE526828

GE80828

GO:0000122

GO:0001656

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0006260

GO:0006275

GO:0006351

GO:0006355

GO:0007417

GO:0007507

GO:0007517

GO:0007623

GO:0008289

GO:0010628

GO:0010629

GO:0012501

GO:0019904

GO:0030154

GO:0030182

GO:0030855

GO:0030903

GO:0032922

GO:0042476

GO:0043065

GO:0043226

GO:0043425

GO:0043433

GO:0045662

GO:0045668

GO:0045892

GO:0046983

GO:0048511

GO:0048856

GO:0072750

GO:0098772

GO:0140416

GO:1901707

HMNXSV003011957

ILMN_1732296

PH_hs_0035462

TC01002347.hg

X69111_at

g10835060_3p_a_at

Participates

as a member of

ID1, ID3 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_002158.3

OpenTargets

ENSG00000117318

GeneCards

Q02535

HPA

ENSG00000117318-ID3

Ensembl

ENSP00000489102, ENSG00000283060, ENSG00000117318, ENST00000374561, ENST00000634790, ENSP00000363689

PRO

Q02535

Pharos - Targets

Q02535

HMDB Protein

HMDBP10740

PDB

2LFH

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q99081 TCF12	1	TCF12 [nucleoplasm] (R-HSA-445670)	0.742	5
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.666	4
UniProt:P15923 TCF3	2	TCF3 [nucleoplasm] (R-HSA-3209896) p-S139-TCF3 [nucleoplasm] (R-HSA-3209894)	0.556	3
UniProt:O43559 FRS3	3	p-5Y-FRS3 [plasma membrane] (R-HSA-191475) FRS3 [plasma membrane] (R-HSA-191482) p-Y-FRS3 [plasma membrane] (R-HSA-9032427)	0.556	3
UniProt:P51149 RAB7A	7	RAB7A [secretory granule membrane] (R-HSA-6804969) RAB7A [plasma membrane] (R-HSA-6804990) RAB7A [cytosol] (R-HSA-8870415) RAB7A [phagocytic vesicle membrane] (R-HSA-9636586) RAB7A [lysosomal membrane] (R-HSA-2213231) GGC-RAB7A [cytosol] (R-HSA-8870438) GGC-RAB7A [lysosomal membrane] (R-HSA-8877454)	0.556	3
UniProt:A6NI15 MSGN1	1	MSGN1 [nucleoplasm] (R-HSA-9793376)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [extracellular region] (R-HSA-6806206) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [cytosol] (R-HSA-373639)	0.556	3
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.556	3
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.556	3