FOXO-mediated transcription

Stable Identifier
R-HSA-9614085
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this pathway in the Pathway Browser

The family of FOXO transcription factors includes FOXO1, FOXO3, FOXO4 and FOXO6. FOXO transcription factors integrate pathways that regulate cell survival, growth, differentiation and metabolism in response to environmental changes, such as growth factor deprivation, starvation and oxidative stress (reviewed by Accili and Arden 2004, Calnan and Brunet 2008, Eijkelenboom and Burgering 2013).

Literature References
PubMed ID Title Journal Year
23325358 FOXOs: signalling integrators for homeostasis maintenance

Eijkelenboom, A, Burgering, BM

Nat. Rev. Mol. Cell Biol. 2013
15137936 FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

Accili, D, Arden, KC

Cell 2004
18391970 The FoxO code

Calnan, DR, Brunet, A

Oncogene 2008
Participants
Participant Of
Orthologous Events
Authored
Reviewed
Created