Reactome | PMP22 [plasma membrane]

PMP22 [plasma membrane]

Stable Identifier

R-HSA-9615623

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Peripheral myelin protein 22, PMP22_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q16585 SGCB

Expand all

External Reference Information

External Reference

UniProt:Q01453 PMP22

Gene Names

PMP22, GAS3

Chain

chain:1-160

Reference Genes

BioGPS Gene:5376 PMP22

COSMIC (genes):PMP22 PMP22

CTD Gene:5376 PMP22

dbSNP Gene:5376 PMP22

ENSEMBL:ENSG00000109099 PMP22

HGNC:9118 PMP22

KEGG:hsa:5376 PMP22

Monarch:5376 PMP22

NCBI Gene:5376 PMP22

OMIM:601097 PMP22

UCSC:Q01453 PMP22

Reference Transcript

Other Identifiers

11715585_a_at

11728274_a_at

16841561

16841575

16841579

210139_PM_s_at

210139_s_at

243050_PM_at

243050_at

3746575

3746576

3746577

3746578

3746579

3746580

3746581

3746582

3746583

3746584

3746585

3746586

3746587

3746588

3746593

3746594

3746595

3746596

3746597

3746598

3746599

3746600

3746601

3746602

3746603

3746604

3746605

3746610

3746612

3746613

38653_at

5376

73050_at

73096_at

79550_at

8012896

8012906

A_21_P0009185

A_23_P100711

A_33_P3274930

D11428_at

GE57050

GE712036

GE772154

GO:0005515

GO:0005886

GO:0005923

GO:0006915

GO:0007268

GO:0007399

GO:0007422

GO:0008285

GO:0010977

GO:0016020

GO:0030154

GO:0032060

GO:0032288

GO:0042552

GO:0043218

GO:0045202

GO:0048856

HMNXSV003008049

HMNXSV003034304

HMNXSV003055957

Hs.193864.0.A1_3p_at

ILMN_1659312

ILMN_1785646

ILMN_1810864

ILMN_1884910

PH_hs_0024203

PH_hs_0033680

TC17001157.hg

TC17001158.hg

TC17001160.hg

TC17002504.hg

U08049_at

U08096_at

g182984_3p_a_at

p6695

Participates

as an output of

PMP22 gene expression (Homo sapiens)

Cross References

RefSeq

NP_696997.1, NP_696996.1, NP_001268385.1, NP_001268384.1, NP_000295.1

OpenTargets

ENSG00000109099

ENSEMBL

ENST00000612492, ENST00000674868, ENSP00000484631, ENSP00000502310, ENST00000675350, ENST00000675819, ENSP00000502835, ENST00000675808, ENSP00000502018, ENSP00000501557, ENSP00000501804, ENSP00000501727, ENSP00000502601, ENSP00000501546, ENST00000674673, ENST00000675950, ENSG00000109099, ENSP00000308937, ENST00000312280, ENST00000676221, ENST00000674651

GeneCards

PMP22

HPA

ENSG00000109099-PMP22

PRO

Q01453

Pharos - Targets

Q01453

GlyGen

Q01453

Orphanet

PMP22

Interactors (59)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BZL3 SMIM3			0.805	9
UniProt:P26715 KLRC1	1	KLRC1 [plasma membrane] (R-HSA-3006545)	0.718	6
UniProt:P40198 CEACAM3	2	CEACAM3 [specific granule membrane] (R-HSA-6806076) CEACAM3 [plasma membrane] (R-HSA-197706)	0.556	3
UniProt:Q9H3N1 TMX1			0.556	3
UniProt:P48165 GJA8	1	GJA8 [endoplasmic reticulum membrane] (R-HSA-190702)	0.556	3
UniProt:Q8IV31 TM139			0.556	3
UniProt:P56856 CLDN18	2	CLDN18 [plasma membrane] (R-HSA-432972) CLDN18 [cell junction] (R-HSA-434607)	0.556	3
UniProt:Q3SXP7 SHSL1			0.556	3
UniProt:P38484 IFNGR2	1	IFNGR2 [plasma membrane] (R-HSA-629620)	0.556	3
UniProt:P07307-3 ASGR2			0.556	3
UniProt:Q9NZD1 GPC5D			0.556	3
UniProt:Q9NY72 SCN3B	1	SCN3B [plasma membrane] (R-HSA-197921)	0.556	3
UniProt:P48051 KCNJ6	1	KCNJ6 [plasma membrane] (R-HSA-975242)	0.556	3
UniProt:Q9GZW8 MS4A7			0.556	3
UniProt:O75787 ATP6AP2	3	ATP6AP2 [plasma membrane] (R-HSA-2022356) ATP6AP2 [ficolin-1-rich granule membrane] (R-HSA-6800921) ATP6AP2 [tertiary granule membrane] (R-HSA-6799717)	0.556	3
UniProt:Q07108 CD69			0.556	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3
UniProt:O15173 PGRMC2	4	PGRMC2 [nuclear envelope] (R-HSA-9707674) PGRMC2 [nucleoplasm] (R-HSA-9707859) PGRMC2 [endoplasmic reticulum membrane] (R-HSA-9714349) PGRMC2 [endosome membrane] (R-HSA-9715090)	0.556	3
UniProt:O15552 FFAR2	1	FFAR2 [plasma membrane] (R-HSA-443944)	0.556	3
UniProt:Q16585 SGCB	3	SGCB [plasma membrane] (R-HSA-9630718) SGCB [Golgi membrane] (R-HSA-9913180) SGCB [endoplasmic reticulum membrane] (R-HSA-9913185)	0.556	3
UniProt:O15554 KCNN4	1	KCNN4 [plasma membrane] (R-HSA-977543)	0.556	3
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:O00501 CLDN5	2	CLDN5 [cell junction] (R-HSA-421264) CLDN5 [plasma membrane] (R-HSA-419991)	0.556	3
UniProt:Q15125 EBP	1	EBP [endoplasmic reticulum membrane] (R-HSA-195697)	0.556	3
UniProt:Q92838 EDA	1	EDA [plasma membrane] (R-HSA-5667156)	0.556	3
UniProt:P54219-3 P542193			0.556	3
UniProt:Q9HBV2 SACA1			0.556	3
UniProt:P27105 STOM	4	STOM [specific granule membrane] (R-HSA-6799569) STOM [plasma membrane] (R-HSA-6806258) STOM [azurophil granule membrane] (R-HSA-6800997) STOM [tertiary granule membrane] (R-HSA-6800960)	0.556	3
UniProt:Q96MV1 TLCD4			0.556	3
UniProt:P31431 SDC4	20	HS(4)-SDC4 [plasma membrane] (R-HSA-2076670) HS(6)-SDC4 [plasma membrane] (R-HSA-2076633) HS(2)-SDC4 [plasma membrane] (R-HSA-2076694) HS(1)-SDC4 [plasma membrane] (R-HSA-2076653) HS(3)-SDC4 [plasma membrane] (R-HSA-2076674) HS(5)-SDC4 [plasma membrane] (R-HSA-2076635) Gal-Xyl-SDC4 [Golgi lumen] (R-HSA-2064249) Gal-Gal-Xyl-SDC4 [Golgi lumen] (R-HSA-2064100) XylS-SDC4 [Golgi lumen] (R-HSA-2064195) SDC4 [Golgi lumen] (R-HSA-2054111) GlcA-Gal-Gal-Xyl-SDC4 [Golgi lumen] (R-HSA-2064067) HS(5)-SDC4 [Golgi lumen] (R-HSA-2076510) HS(6)-SDC4 [Golgi lumen] (R-HSA-2076330) HS(4)-SDC4 [Golgi lumen] (R-HSA-2076407) HS(3)-SDC4 [Golgi lumen] (R-HSA-2076418) HS(2)-SDC4 [Golgi lumen] (R-HSA-2076411) HS(1)-SDC4 [Golgi lumen] (R-HSA-2076434) Heparan(4)-SDC4 [Golgi lumen] (R-HSA-2076613) Heparan(3)-SDC4 [Golgi lumen] (R-HSA-2076460) Heparan(2)-SDC4 [Golgi lumen] (R-HSA-2076446)	0.556	3
UniProt:Q96CE8 T4S18			0.556	3
UniProt:Q9Y282 ERGI3			0.556	3
UniProt:O15529 GPR42			0.556	3
UniProt:P60508 SYCY2			0.556	3
UniProt:Q8WXH2 JPH3			0.556	3
UniProt:Q9NUH8 TM14B			0.556	3
UniProt:Q13113 PDZ1I			0.556	3
UniProt:P35372-10 OPRM1			0.556	3
UniProt:P41181 AQP2	3	AQP2 [transport vesicle membrane] (R-HSA-432215) p-S256-AQP2 [transport vesicle membrane] (R-HSA-432222) p-S256-AQP2 [plasma membrane] (R-HSA-432231)	0.556	3
UniProt:O95236-2 APOL3			0.556	3
IntAct:EBI-22326698 CCSB ORF ID			0.556	3
UniProt:Q9BZJ8 GPR61			0.556	3
UniProt:P09693 CD3G	3	p-Y160,Y171-CD3G [plasma membrane] (R-HSA-202362) CD3G [plasma membrane] (R-HSA-197917) CD3G [clathrin-coated endocytic vesicle membrane] (R-HSA-8869080)	0.556	3
UniProt:Q3MIR4 CC50B			0.556	3
UniProt:Q96HE8 TMM80			0.556	3
UniProt:Q2HXU8-2 CLEC12B			0.556	3
UniProt:Q96DZ7 T4S19			0.556	3
UniProt:O43889-2 CREB3			0.556	3
UniProt:O95859 TSN12			0.556	3
UniProt:Q8N9I0 SYT2	3	SYT2 [synaptic vesicle membrane] (R-HSA-194786) SYT2 [plasma membrane] (R-HSA-168795) SYT2 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869116)	0.556	3
UniProt:Q86T13 CLC14			0.556	3
UniProt:P55899 FCGRN			0.556	3
UniProt:P19397 CD53	3	CD53 [tertiary granule membrane] (R-HSA-6804799) CD53 [plasma membrane] (R-HSA-6804817) CD53 [specific granule membrane] (R-HSA-6804793)	0.556	3
UniProt:P56747 CLDN6	2	CLDN6 [plasma membrane] (R-HSA-419992) CLDN6 [cell junction] (R-HSA-421250)	0.556	3
UniProt:Q9H2H9 SLC38A1	1	SLC38A1 [plasma membrane] (R-HSA-212663)	0.556	3
UniProt:Q5JX71 F209A			0.556	3
UniProt:Q9H6H4 REEP4			0.556	3
UniProt:P54849 EMP1			0.556	3
UniProt:Q6UWD8 CP054			0.556	3

Cite Us!