All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene

Stable Identifier
R-HSA-9617067
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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The RARA:RXR heterodimeric retinoic acid receptor binds a retinoic acid receptor element (RARE) in the promoter of the CEBPE gene (Park et al. 1999). Retinoic acid binds RARA:RXR at the CEBPE gene and activates transcription of CEBPE (Park et al. 1999).

Literature References
PubMed ID Title Journal Year
10330422 CCAAT/enhancer binding protein epsilon is a potential retinoid target gene in acute promyelocytic leukemia treatment

Park, DJ, Chumakov, AM, Vuong, PT, Chih, DY, Gombart, AF, Miller, WH, Koeffler, HP

J. Clin. Invest. 1999
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Orthologous Events
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