EP300,CREBBP bind SOH-C481-FOXO4

Stable Identifier
R-HSA-9617683
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

After oxidation of FOXO4 cysteine residues by reactive oxygen species (ROS), FOXO4 forms a complex with a protein acetyltransferase EP300 (p300) or CREBBP (CBP). A covalent disulfide bond between FOXO4 and EP300 or CREBBP facilitates complex formation (Dansen et al. 2009).

Participants
Participant Of
Inferred From
Authored
Reviewed
Created