KAT2B,EP300 acetylate FOXO3 under oxidative stress

Stable Identifier
R-HSA-9620515
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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KAT2B (PCAF) and possibly EP300 (p300) acetylate FOXO3 under conditions of oxidative stress (Brunet et al. 2004).

Literature References
PubMed ID Title Journal Year
14976264 Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

Brunet, A, Sweeney, LB, Sturgill, JF, Chua, KF, Greer, PL, Lin, Y, Tran, H, Ross, SE, Mostoslavsky, R, Cohen, HY, Hu, LS, Cheng, HL, Jedrychowski, MP, Gygi, SP, Sinclair, DA, Alt, FW, Greenberg, ME

Science 2004
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
peptide-lysine-N-acetyltransferase activity of KAT2B,(EP300) [nucleoplasm]
Physical Entity
Activity
This event is regulated
Positively by
Orthologous Events
Authored
Reviewed
Created