BTG1 gene expression is stimulated by FOXO3

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R-HSA-9620915
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Reaction [omitted]
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Homo sapiens
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Transcription of the BTG1 gene, encoding antiproliferative Protein BTG1 is directly stimulated by FOXO3 (Bakker et al. 2004, Bakker et al. 2007, Wang et al. 2015). BTG1 inhibits the outgrowth of erythroid colonies and promotes maturation of mouse (Bakker et al. 2004) and human (Wang et al. 2015) erythroid cells.

Literature References
PubMed ID Title Journal Year
25843800 Knockdown of transcription factor forkhead box O3 (FOXO3) suppresses erythroid differentiation in human cells and zebrafish

Wang, H, Li, Y, Wang, S, Zhang, Q, Zheng, J, Yang, Y, Qi, H, Qu, H, Zhang, Z, Liu, F, Fang, X

Biochem. Biophys. Res. Commun. 2015
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