FOXO1 binds NPY gene promoter

Stable Identifier
R-HSA-9622980
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
FOXO1 binds NPY gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
In the hypothalamic orexigenic neurons FOXO1 binds to the insulin responsive elements (IREs) in the promoter of the NPY gene (Kim et al. 2006), encoding neuropeptide-Y .
Literature References
PubMed ID Title Journal Year
16783365 Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis

Park, JY, Kim, YB, Kim, HS, Won, JC, Pak, YK, Jang, PG, Lee, KU, Namkoong, C, Kim, KS, Choi, YS, Kim, SW, Kim, MS

Nat. Neurosci. 2006
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2018-10-11)
Reviewed
Bertaggia, E  (2018-10-26)
Donlon, T  (2018-10-17)
Created
Orlic-Milacic, M  (2018-10-02)
Cite Us!